Although SCAD is idiopathic in the majority of patients, an association has been described with
fibromuscular dysplasia (FMD); [9] there are also case reports of SCAD in patients with HIV.
Anderson, "Angiographic spectrum of cervical and intracranial
fibromuscular dysplasia," Stroke, vol.
The United States Registry for
Fibromuscular Dysplasia: results in the first 447 patients.
Surgical excision of the abnormal right brachial artery with reconstruction and angioplasty has had success in patients with brachial artery disease related to
fibromuscular dysplasia [8,9].
Cross-sectional imaging also plays a major role in diagnosing other vascular conditions manifesting with unilateral neck pain and mimicking IC, such as arterial dissection, large vessel arteritis, arteriosclerosis,
fibromuscular dysplasia, or aneurysms.
Included in the differential diagnosis are inflammatory arteritis, collagen vascular disease, mycotic aneurysms, cystic medial necrosis seen in type IV Ehlers Danlos and Marfan's syndrome, and
fibromuscular dysplasia (FMD) which are also important to consider [6, 7].
Renovascular hypertension is most commonly caused by artherosclerosis or
fibromuscular dysplasia. However, it may also be caused by extrinsic compression of the renal vessels.
Inheritance of arterial lesions in renal
fibromuscular dysplasia. J Hum Hypertens 2007;21:393-400.
In our patient there was circumferential narrowing involving post ductal part of descending aorta and similar changes were seen in subclavian and left common carotid artery suggestive of Takayasu Arteritis with
fibromuscular dysplasia. Her ejection fraction was 60%.No other associated anomaly was found.
The most common changes seen in renal arteries are
fibromuscular dysplasia and atherosclerosis (1).
Kim also notes that SCAD is more common in people with
fibromuscular dysplasia (FMD), which causes some arteries to narrow and others to develop an aneurysm--a bulge that can weaken the walls of a blood vessel.
Fibromuscular dysplasia of the internal carotid artery.
In the remaining 10% of cases, the cause is
fibromuscular dysplasia (FMD).
Other etiological factors include arteritis, neurofibromatosis,
fibromuscular dysplasia, radiation, posttraumatic scarring and compression syndromes (2-5).
Fibromuscular dysplasia associated with simultaneous spontaneous dissection of four peripheral arteries in a 30-year-old man.