Tissue sections were deparaffinized in xylene and dehydrated in graded ethanol series, washed with distilled water, and then placed in a pressure cooker in Tris-EDTA buffer pH 8.9 for 5 minutes at 95[degrees]C (CD 95, Fas ligand
, Ki-67, and BCL-2) or citrate buffer pH 6.0 (BID, MCL-1, and p27).
Lee et al., "Membrane-bound Fas ligand
only is essential for Fas-induced apoptosis," Nature, vol.
As shown in Table 3, NCOR2 and ZNRD1 are coexpressed with 356 (FASLG; Fas ligand
) and 6772 (STAT1; signal transducer and activator of transcription 1) in the measles pathways.
Treatment with the GSK-3[beta] inhibitor VIII did not change Fas or Fas ligand
immunoreactivity (IR) under serum-deprived conditions (Figures 3(a) and 3(b), resp.).
CKD = chronic kidney disease, (Me; 25-75%) = median and interquartile range, IL-1[beta] = interleukin 1[beta], TNF-RI = soluble tumor necrosis factor receptor I, TNF-RII = soluble tumor necrosis factor receptor II, sFasL = soluble Fas ligand
, sFas = soluble Fas, sICAM-1 = soluble intercellular adhesion molecule-1, TIMP-1 = tissue inhibitor of metalloproteinase-1, sVCAM-1 = soluble human vascular cell adhesion molecule-1, MMP-9 = metalloproteinase-9, and TGF-[beta]1 = transforming growth factor-beta 1.
Herrera-Esparza, "Glomerular expression of Fas ligand
and Bax mRNA in lupus nephritis," Autoimmunity, vol.
In fact, neutrophils appear to play a vital role in inducing pulmonary epithelial cell apoptosis via the release of soluble FAS ligand
; the administration of an inhibitory anti-FAS antibody could block the epithelial cell apoptosis (32).
Regulation of fas ligand
expression during activation-induced cell death in T cells by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase.
The signals of Fas ligand
(FasL) or agonist antibodies are transduced by intracellular death domains that interact with adapter molecules, which are conserved among the TNF receptor super family (TRAIL-DR4/DR5, TNFR1).
A subset of 5 markers was associated with insulin sensitivity (assessed using the dynamic CISI measure): fasting glucose, insulin, Fas ligand
, complement C3, and PAI-1.
"We found an explanation for why binding of Fas ligand
is not enough to initiate DISC formation and set cell death in motion.
and the fate of antitumor cytotoxic T lymphocytes.
Methods: Soluble Fas (sFas) antigen and Fas ligand
levels in plasma samples from 39 antiretroviral treatment naive patients was estimated and compared with T cell subsets and HIV-1 viral load.
was significantly decreased levels following 15 and 30 minutes stimulation; Fas receptor decreased at all time points.
The aim of this study was to determine the changes in complete blood count (CBC), NK cell count and activity, perforin expression, and Fas and soluble Fas ligand
(sFas-L) levels in immunocompetent children with VZV infection and define any possible relations between the levels and development of varicella complications.