Private practice: Julie Malan, Registered Genetic Counsellor, tel: 082 553 5891 Familial Cancer
Clinic at Femina Hospital, tel: 021 328 2676
syndromes are defined clinically by the presence of recurring clusters of specific types of cancer in families (Eng, Hampel, & de la Chapelle, 2001).
The following example of familial cancer
risk counseling illustrates the recent emergence of a new interdisciplinary area of practice.
risk part II: Breast cancer risk counseling and genetic susceptibility testing.
Analyzes the latest innovations in pharmacogenomics and covers the major applications for familial cancer
, breast cancer, colon cancer and lung cancer.
She is a founder member of the South African HPV Advisory Board and its research fund and of the University of Pretoria and Netcare Familial Cancer
Centre, and established the Southern African Journal of Gynaecological Oncology, of which she is still Editor-in-Chief.
Eisen is one of the study's authors and head of the Familial Cancer
Program at Sunnybrook.
Previous research has documented that most primary care patients do not receive adequate assessment of familial cancer
8 times and, thus, the lowest risk elevation in the familial cancer
Melanoma and breast cancer are fairly common bedfellows in familial cancer
syndromes, and both types of cancer have been linked with mutations in cyclin-dependent kinase inhibitor 2A, a tumor suppressor gene, in some studies of familial cancer
A woman who gives a history of multiple cases of breast/ovarian cancer in two or more generations (see Figure 2) may need to be referred to a multidisciplinary center that provides a coordinated approach to familial cancer
risk counseling and genetic testing.
In the past, physicians had to rely on a family history that suggested a risk of this familial cancer
Researchers examined the 16INK4A gene because of its suspected role in the progression of retinoblastoma and its involvement in a predisposition to familial cancer
1 issue and subsequent issues, we will cover specific topics of interest to the practicing internist, including pharmacogenetics, use of electronic family history tools, familial cancer
syndromes, evaluation of patients with joint laxity, and genetic testing in cardiovascular disease.
For example, if a patient's grandmother had breast cancer when she was 65, an aunt had cervical cancer at age 25, and an uncle had lung cancer because he smoked, that may indeed be a strong family history of cancer, but when you ask if this is consistent with a familial cancer
syndrome, it is not," Dr.