The postsynaptic NMDA-receptor-PSD-95 signaling complex in excitatory synapses
of the brain.
2012) LIS1-dependent retrograde translocation of excitatory synapses
in developing interneuron dendrites.
The role of synaptic plasticity at excitatory synapses
is established for such adaptations.
When enough excitatory synapses
are activated simultaneously, the neuron conducts a regenerative electrical wave of depolarization along its axon.
Because the excitatory synapses
that we are studying form their connections right after birth in humans, we think these specific pathways may even provide an opportunity for early intervention after birth," Soderling said.
The excitatory synapses
show both synaptic active sites and postsynaptic densities, as can be observed in Fig.
Presynaptic protein complexin I is a marker of inhibitory synapses, and complexin II is a marker of excitatory synapses
Lewis believes that these changes occur because axon terminals containing excitatory synapses
are eliminated during puberty.
The results we obtain will be useful to rationally interfere with excitatory synapses
in the brain and may therefore help the development of therapies.