21 Any increase in the inhibition zone towards the disc of amoxicillin/clavulanic acid was considered as positive result for ESBL
Beta-lactamase production, efflux mechanisms, Amp-C lactamases and loss of porin by gram-negative bacteria is the cause of resistance and have become a serious concern.10 The current study was planned to find the most suitable antibiotic against UTI caused by ESBL-producing uropathogens, and to see the epidemiology of ESBL
This study aimed to find out the characterization of Enterobacteriaceae and antibiotic sensitivity patterns with special reference to detection of ESBL
producing Enterobacteriaceae in patients in a tertiary care hospital in south Kerala.
PCR amplification showed that ESBL-producing isolates harbored a large amount of ESBL
We performed whole-genome sequencing for 1 ESBL
producing group I (class A) microorganism are inhibited by clavulanic acid and for such type of stains third generation of cephalosporins along with clavulanic acid can be used as confirmatory test (Kang HY et al., 2005).
(4) In addition, extensive use of these drugs leads to mutations of ESBL
genes and the emergence of ESBL
All strains which were resistant for Cefotaxime and Ceftriaxone were selected for checking the ESBL
production by DDST and MDDST.
Detection of extendedspectrum [beta]-lactamase (ESBL
) and plasmid-borne blaCTX-M and blaTEMgenes among clinical strains of Escherichia coli isolated from patients in the north of Iran.
A previous study in Libya showed ESBL
prevalence among the predominant uropathogens E.
Resistance To Never Beta-lactams and Related ESBL
Types in Gram-negative Nosocomial Isolates in Turkish Hospitals: Results of the Multicentre Hitit Study.
coli urine isolates, to phenotypically assess the ESBL
carriage of these isolates and to characterize the ESBL
genotypes of these isolates.
A total of 45 nonduplicate, consecutive, phenotypically confirmed ESBL
isolates identified in the Microbiology Laboratory from June-July 2016 were studied.
Because Enterobacteriaceae organisms are becoming increasingly resistant to standard therapy, treatment selected by interpretation of MICs of ESBL
producers and by clinical outcome may offer therapeutic alternatives in more challenging situations [7, 12-14].
The production of ESBL
leads to multidrug resistance in Salmonella enterica isolates.