In Turku University Central Hospital, coding of drug effects
in clinical chemistry was started in 1995 when a DLE code was developed (9).
As for neonatal toxicity direct drug effects
and withdrawal syndrome occurred in some neonates whose mothers took tricyclics, fluoxetine, and SSRIs near term.
This valuable resource provides simple explanations of the ways in which biological systems use basic biochemical mechanisms to produce fine chemical control of physiology, allowing for more informed predictions of drug effects
in all systems and forming the basis of the drug-discovery process.
The syndrome doesn't include outbursts that stem from other mental disorders or from alcohol or drug effects
The book is not intended as a text of adverse drug reactions, clinical pharmacology, or epidemiology; rather, it is intended to elucidate the methods of investigating adverse drug reactions, as well as other questions of drug effects
Serious adverse drug effects
in patients led to the withdrawal or restriction of four quinolones in the past decade (temafloxacin, grepafloxacin, trovafloxacin, and sparfloxacin).
Aside from the unnecessary distress and inconvenience suffered by the 60 patients who experienced preventable adverse drug effects
at Brigham & Women's Hospital during the course of another 1997 study, the expense of their treatment -- almost five days added to their stays in the hospital -- was inflated by close to $6,000 each.
As for neonatal toxicity, direct drug effects
and withdrawal syndrome occurred in some neonates whose mothers took tricyclics, fluoxetine, or newer SSRIs near term.
This involves identifying drug effects
by associative changes in microRNA expression profiles and their analysis in context against a growing proprietary database of known drug responses.
For studies of drug effects
on behavior, anesthesia is no alternative.
HIV-TB co-infection often results in increased frequency of adverse drug effects
, which may reduce compliance and increase induction of drug resistance.
Nucleic acid based toxicity biomarkers discovered through this process may assist in the early detection of toxic drug effects
and may therefore enable such drug candidates not to progress into more expensive drug development stages.
In contrast, orange juice extracts didn't contain bergamottin at all--in accordance with the observation that orange juice doesn't cause the same drug effects