agonist

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Synonyms for agonist

the principal character in a work of fiction

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someone involved in a contest or battle (as in an agon)

a muscle that contracts while another relaxes

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(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction

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References in periodicals archive ?
The addition of Azilect to levodopa or dopamine agonist therapy in our claims analysis is in line with interviewed physicians' practice of adding drugs to the existing drug regimen of a Parkinson's disease patient when an adjustment to the treatment regimen is required, and these findings confirm that Azilect is considered an appropriate therapy for such use," said Decision Resources Analyst Nadja Rozovsky, Ph.
For example, in one study, researchers observed a "huge increase" in sedation effects--a decrease in sleep latency--about 3-5 hours after 12 healthy volunteers took a dopamine agonist (Br.
Dopamine agonists are now first-line therapy for restless legs syndrome, and although the doses used are generally considerably lower than in Parkinson's, some emerging evidence suggests that treated RLS patients may also have an increased prevalence of ICDs (Parkinsonism Relat.
4) Conventional antipsychotic agents are commonly associated with elevated prolactin due to dopamine agonist activity.
His dopamine agonist was changed from pramipexole to ropinerole at 4 mg tid as a trial, in an attempt to further decrease his dyskinesias.
Larger epidemiologic studies in these other populations are needed to examine the possible relationships between dopamine agonist treatment, other clinical features and impulse control disorders," they concluded.
However, "we shouldn't be firmly stating use of a dopamine agonist or levodopa.
Prescribe levodopa for older and dopamine agonists for younger patients.
MADRID -- Patients with a cardiovascular abnormality who also take an ergotamine-derived dopamine agonist are at an increased risk for a worsening of their heart problems.
Two Cochrane reviews found that patients who tolerated the dopamine agonist bromocriptine--when administered alone or with levodopa--had delayed dyskinesias and motor complications compared with levodopa alone.
A dopamine agonist is often the next choice and may be used as monotherapy, or it may be added to levodopa when response to levodopa is insufficient.
16 January 2012 - Japan's Otsuka Pharmaceutical Co Ltd, a company of Otsuka Holdings Co Ltd (TYO:4578), said on Friday it had applied for approval last month of the dopamine agonist transdermal patch, Rotigotine Patch, in Japan.
This first-in-class innovative chimeric compound bears within a single molecule two pharmacological moieties, a somatostatin analog and a dopamine agonist, which act synergistically following activation of those receptors in disorders such as acromegaly and neuroendocrine tumours.
In one report, 1,356 of 3,006 fibromyalgia patients had taken at least one dose of a dopamine agonist, and 21 developed compulsive gambling, shopping, or both after taking a mean of 4.
Cycloset is taken by mouth once daily in the morning, and results in a "brief pulse of dopamine agonist activity shortly after its administration," which improves postprandial glucose without increasing plasma insulin concentrations, according to a statement issued by VeroScience.