Opioids included in the REMS plan include methadone (Dolophine
), and the morphine formulations MS Contin, Kadian, Avinza, Embeda, Oramorph, oxycodone (OxyContin), hydromorphone (Exalgo), transdermal fentanyl (Duragesic), buprenorphine (Bu-trans), and oxymorphone (Opana ER).
FDA experts say extended-release and long-acting opioids--including OxyContin, Avinza, Dolophine
, Duragesic, and eight other brand names are extensively misprescribed, misused and abused, leading to overdoses, addiction and even deaths across the United States.
For maintenance-phase opiate use disorder treatment, we see buprenorphine (Buprenex, Subutex, Transtec), methadone (Dolophine
, Methadose, Metharose, and others) and the buprenorphine/naloxone (Suboxone) combination.
The methadone hydrochloride tablets are the generic equivalent of Dolophine
hydrochloride 10-mg tablets.
Silver Spring, MD 20993 Medicine Active Ingredient Actiq, oral transmucosal lozenge Fentanyl Citrate Avinza, capsules (extended release) Morphine Sulfate Daytrana, transdermal patch system Methylphenidate Demerol, tablets * Meperidine Hydrochloride Demerol, oral solution * Meperidine Hydrochloride Diastat/Diastat AcuDial, rectal gel Diazepam Dilaudid, tablets * Hydromorphone Hydrochloride Dilaudid, oral liquid * Hydromorphone Hydrochloride Dolophine
Hydrochloride, tablets * Methadone Hydrochloride Duragesie, patch (extended release) Fentanyl * Embeda, capsules (extended release) Morphine Sulfate; Naltrexone Hydrochloride Fentora, tablets (buccal) Fentanly Citrate kadian.
Important interactions between Kaletra and other agents, including rifabutin (Mycobutin), disulfiram (Antabuse), metronidazole (Flagyl), methadone (Dolophine
) and corticosteroids, may require adjusted dosing of either drug and are noted in Kaletra's package insert.
Some examples of medications in this category include codeine, propoxyphene (Darvon or Darvocet), oxycodone (Percocet, Tylox, Roxiprin), pentazocine (Talwin), hydrocodone (Vicodin), and methadone (Dolophine
In 1988, HQ finally threw caution to the winds and published a straight-forward Drug Dosage Table listing the lethal dosages of eighteen common prescription drugs: Amytal, Butisol, Valium, Dalmane, Doriden, Noctec, Dilaudid, Miltown, Noludar, Demerol, Dolophine
, Norflex, Seconal, Nembutal, Darvon, codeine, morphine, and phenobarbital.