10) Botulinum toxin type A, injected directly into the detrusor muscle
, can be as effective as medication in patients with urinary urge incontinence.
The tumour cells were also seen in sheets invading into the detrusor muscle
Estrogen levels influence beta-3-adrenoceptor-mediated relaxation of the female rat detrusor muscle
Acting on the detrusor muscle
, anticholinergic drugs can relieve muscle spasms, reduce bladder pressure, and relieve symptoms in the urine storage period.
The detrusor muscle
is innervated by fibers from 2nd, 3rd, and 4th sacral roots; hence, any lesion in the region or lumbar spinal surgery (as seen in this patient) may lead to neurogenic bladder.
There are two types of overflow incontinence: In one, the neck of the bladder is obstructed, most commonly by an enlarged prostate in men; in the other, the detrusor muscle
is underactive; in both types, the bladder fills with urine, then overflows.
This in-office procedure --involving some 20 injections into the detrusor muscle
(the muscle on your bladder wall that contracts to expel urine)--takes just five to 10 minutes, with results lasting six to 12 months.
ApexM, for women with urgency and mixed urinary incontinence, provides alternating-frequency stimulation to strengthen the pelvic floor muscles and calm detrusor muscle
Dose of 100-300 U of botulinum toxin is reconstituted in 20-30ml sterile saline and is injected into the detrusor muscle
below the bladder mucosa avoiding the trigone.
These results were achieved with a single dose of Dysport 750 Units injected in either 15 or 30 sites in the detrusor muscle
This diagnostic assessment allows each child to be categorised into one of four subtypes of neuropathic bladder dysfunction based on sphincter and detrusor muscle
activity (Table 1).
Overactive bladder (OAB) symptoms occur during the storage and filling phases of urination during which the OAB experiences involuntary contractions of the detrusor muscle
The condition occurs when the bladder's detrusor muscle
contracts while the bladder fills with urine, when it should remain at rest.
Urinary retention is a common post-operative complication and is associated with bladder distension, risking permanent detrusor muscle
damage (Keita et al.
Carbachol induced contractions of isolated strips of rat detrusor muscle
in a dose-dependent manner in both groups.