Delayed Type Hypersensitivity
Assay: On day 1, drugs were administered to treated groups.
Delayed type hypersensitivity
(DTH) is a reaction triggered by antigen-specific T cells that can be induced by different allergens.
The Th-1 cells secrete interferon-gamma (IFN-[alpha]), interleukin-2 (IL-2) and tumour necrosis factor-beta (TNF-[beta]) and are responsible for cell-mediated inflammatory reactions, delayed type hypersensitivity
and tissue injury in infections and autoimmune diseases.
The delayed type hypersensitivity
(DTH) reaction was evaluated by the footpad swelling test as described previously .
He pursued the basis of this reaction with a long chain of students and post doctoral scientists to show that it differed from the classical delayed type hypersensitivity
both in kinetics and in regulatory aspects.
Some reports suggest that the lesions are the result of a delayed type hypersensitivity
Lastly, the Enzyme Linked Immunosorbent Assay (ELISA) identifies antibodies associated with both immediate and delayed type hypersensitivity
reactions and is therefore more comprehensive than skin testing or the RAST method.
02:45 DETERMINATION OF THE ABILITY OF A NUTRITIONAL SUPPLEMENT TO RESTORE THE DELAYED TYPE HYPERSENSITIVITY
IMMUNE RESPONSE IN ETHANOL TREATED LABORATORY RATS.
Additionally, in the NeuVax + Herceptin arm, in vivo HER2-specific T-cell immune responses, assessed by delayed type hypersensitivity
skin testing, showed a time-dependent increase in IR potency compared to the earliest tested datapoint, while no such increase was observed in the control arm.
Cell Mediated Immunity: Cell mediated immunity (CMI) was determined by employing dermis delayed type hypersensitivity
(DHT) reaction (Tiwary and Goel, 1985).
Additionally, the DTH (delayed type hypersensitivity
) response was examined by measuring the footpad swelling of immunized mice.