adenosine

(redirected from Cyclic adenosine monophosphate)
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Words related to adenosine

(biochemistry) a nucleoside that is a structural component of nucleic acids

References in periodicals archive ?
Cyclic adenosine monophosphate response element-binding protein (CREB) is a cellular transcription factor that binds to certain DNA sequences called cyclic adenosine monophosphate response elements and influences transcription of downstream genes.
Further study demonstrated that S[O.sub.2] elevated cellular cyclic adenosine monophosphate (cAMP) production to activate the PKA signaling, subsequently phosphorylated c-Raf on Ser259 site to block its activation, and then inhibited the extracellular regulated protein kinase (Erk)/mitogen-activated protein kinase (MAPK) signaling transduction, which finally prevented cell cycle progression and led to the suppression ofVSMC proliferation [43].
Experiments with cultured human cells also showed that caffeine competitively bound to adenosine receptors, which disrupted signaling of cyclic adenosine monophosphate (cAMP), a key part of the circadian clock, the researchers said.
Elevation of the second messenger cyclic adenosine monophosphate (cAMP) in macrophages suppresses several inflammatory responses, including inflammatory mediator production and receptor-mediated phagocytosis.
Otezla is an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4) specific for cyclic adenosine monophosphate (cAMP).
Bauer, "Microparticles from pulmonary microvascular endothelial cells contain cyclic adenosine monophosphate," Am.
OTEZLA (apremilast) is an oral, small-molecule inhibitor of phosphodiesterase 4 (PDE4) specific for cyclic adenosine monophosphate (cAMP).