disease

(redirected from Crigler-Najjar disease)
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Related to Crigler-Najjar disease: Arias syndrome
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a pathological condition of mind or body

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Abbreviations ALF: Acute liver failure ASL: Arginine succinyl lyase deficiency CND: Crigler-Najjar disease DHT: Domino hepatocyte transplantation DLT: Domino liver transplantation FAP: Familial amyloid polyneuropathy GSD: Glycogen storage disease HCC: Hepatocellular HT: Hepatocyte transplantation DLT: Living donor liver transplantation LT: Liver transplant SLT: Split liver transplantation OLT: Orthotopic liver transplantation OTD: Ornithine transcarbamylase deficiency PFIC: Progressive familial intrahepatic cholestasis TTR: Transthyretin.
Giovanni Ambrosino, MD and colleagues from the University of Padua's First Surgical Department performed the procedure October 11 on a 10-year-old Croatian boy with Crigler-Najjar disease. The mainstay of treatment for this inherited condition, in which the liver fails to produce an enzyme that allows bilirubin to be excreted by the body, is phototherapy-up to 16 hours daily.