Surgical resection was deemed contraindicated owing to the erosion of the tumour directly through the cribriform plate
to the frontal lobe, transgressing the cerebrospinal fluid space.
It extended from cribriform plate
of ethmoid bone upto the rostral end of nasal bone in pig (Hare, 1975c) and up to the level of 2nd transverse rugae of hard palate in sheep (Ganga Naik et al., 2004).
(9) In 1962, Keros studied 450 skulls and described 3 types of olfactory fossas which are formed by cribriform plate
and the fovea ethmoidalis.
Organisms enter through the olfactory neuroepithelium at the level of the cribriform plate
and invade the amyelinic submucosal nervous plexus13.
It enters the nose and traverses the cribriform plate
to enter the brain, causing acute meningoencephalitis.
Spontaneous CSF fistulae are most common in the anterior cranial fossa, at the ethmoid roof and cribriform plate
. Less common sites include the sphenoid sinus, around the sella or at the inferolateral or pterygoid recesses.2
There is a rigid scleral opening and a collagenous cribriform plate
. Myelination is normal beyond the cribriform plate
Radioactively tagged nanoparticles have been shown in rodents to make their way through the nasal cavity, across the cribriform plate
and into the olfactory bulb--part of the brain.
Direct extension from the cribriform plate
can cause necrohemorrhagic lesions in the base of the frontal lobe.
The frontal bone was removed, the bilateral olfactory bulbs were exposed, and the cribriform plate
In the intranasal instillation studies, right and left olfactory bulbs and mucosa (including turbinates and cribriform plate
) were removed.
If unchecked, infection can travel to the brain through the orbital apex, orbital vessels, or cribriform plate
The method of removing the brain by fracturing the cribriform plate
and extracting the organ through the nostrils was probably not employed before the Eighteenth Dynasty. Bourriau and Bashford radiographed a Roman Era mummy (30 BC to 323 AD) in which a missing posterior arch on the right side of the atlas suggested that the brain had been removed through the foramen magnum.
The proposed mechanism of CRVO is related to thrombus formation at the cribriform plate
. Retinal vein occlusions can occur due to a variety of reasons involving local and systemic risk factors along with anatomical anomalies leading to narrowing of the venous lumen, increase in turbulence, endothelial damage and ultimately formation of thrombus4-6.
It is well known that Neisseria meningitides can penetrate the cribriform plate
and reach the meninges causing meningitis.