activity in cerebrospinal fluid in purulent meningitis.
Abnormal biochemical results included severely elevated activities of creatine phosphokinase
(96 019 U/L; International Species Information System [ISIS] reference interval, 130-1143 U/L)1 and aspartate aminotransferase (4349 U/L; ISIS reference interval, 105-415 U/L), (1) indicating severe myocellular damage (Fig 1).
Symptoms included fever, altered level of consciousness, changes in mental status, drooling, diaphoresis, urinary incontinence, sweating, development of tremors, lead pipe rigidity, tachycardia, and increased level of creatine phosphokinase
. His level of consciousness according to the Glasgow coma score (GCS) was 11.
The most common adverse events were diarrhea, occurring in 7% of daptomycin patients and 5% of SOC patients; and increased creatine phosphokinase
, occurring in 6% of daptomycin patients and 5% of SOC patients (Pediatrics.
The text reading "Several studies reported that one night of sleep deprivation can result in metabolic irregularities, such as decreased plasma lactate concentration as well as increased creatine phosphokinase
and myoglobin levels, after a bout of exercise the following morning [55,56]" should be corrected to "Several studies reported that one night of sleep deprivation can result in metabolic irregularities, such as decreased plasma lactate concentration as well as increased creatine phosphokinase
and myoglobin levels, after a bout of exercise the following evening [55, 56]."
 It is a recognized but rare cause of rhabdomyolysis [1, 2]; a clinical syndrome characterized by elevated serum concentrations of creatine phosphokinase
(CPK) and myoglobinuria leading to renal dysfunction .
Blood work was within normal limits apart from an elevated creatine phosphokinase
(CPK) level of 533IU/L (normal range 30-135IU/L) and an elevated serum myoglobin of 494ng/ml (normal range 7.0-46.2 ng/mL).
The following information was obtained from the medical records of each patient: age, sex, clinical symptoms, and signs (such as fever, cough, rhinorrhea, chest pain, palpitation, diarrhea, anorexia or vomiting, tachypnea, weakness, and seizure), microbiology, electrocardiogram (ECG) and echocardiography findings, treatment modalities, complications, long-term outcomes, and laboratory tests such as white blood cell (WBC) counts, C-reactive protein (CRP), creatine phosphokinase
(CK), creatine phosphokinase-MB (CK-MB), troponin-I (Trop-I), blood urea nitrogen (BUN), creatinine (Cr), alanine (ALT) and aspartate aminotransferase (AST), and serum electrolytes.
The results revealed that administration of EESR to rats pre-irradiation significantly reduced the severity of radiation-induced elevation of tumor necrosis factor a, interleukin 1b, interleukin 6 and serum creatine phosphokinase
, lactate dehydrogenase and aspartate amino transferase activities, total cholesterol and low-density lipoprotein-cholesterol levels, high-density lipoprotein-cholesterol, creatine kinase-MB and cardiac troponin 1.
Side effects included increased blood creatine phosphokinase
, myalgia and anaphylactic reactions.
Biochemical parameters like SGOT, SGPT, creatine phosphokinase
, lactate dehydrogenase were markedly raised in the insecticide exposed agriculture workers as compared to control group.
Primary lab results were as follows: serum Na 143 mmol/L, serum K 4.5 mmol/L, white blood cell 19.2 x 10[sup]12/L, Hgb 143 g/L, platelet 164,000/[micro]l, serum creatinine (Cr) 0.012 g/L, blood urea nitrogen (BUN) 0.62 g/L, creatine phosphokinase
(CPK) 2300 U/L, alanine aminotransferase 180 U/L, aspartate aminotransferase 265 U/L, pH 7.28, HCO[sub]3[sup]− 15 mmol/L, and PCO[sub]2 29 mmHg.
Serum uric acid (UA), creatine phosphokinase
and urinary malondialdehyde (MDA) were evaluated.
Clinical and biological findings recorded at admission were associated with severity (Tables 1, 2) as follows: hypotension, chest auscultation abnormalities, icterus, oligo/anuria, bilirubin >49 [micro]mol/L, creatinine >154 [micro]mol/L, creatine phosphokinase
>443 U/L, C-reactive protein >282 mg/L, hemoglobin <12.2 g/dL, lymphocytes <0.49 x [10.sup.9] cells/L, platelets <92 x [10.sup.9]/L, and prothrombin time <68%.
Relationship between elevated creatine phosphokinase
and the clinical spectrum of rhabdomyolysis.