Cox-2 inhibitor

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  • noun

Words related to Cox-2 inhibitor

an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1

References in periodicals archive ?
Although traditional NSAIDs inhibit both TXA[sub]2 and prostacyclin, selective COX-2 inhibitors do not affect TXA[sub]2 synthesis, due to the lack of COX-2 in platelets.
The drugs evaluated by researchers were COX-2 inhibitors, which include celecoxib, rofecoxib, diclofenac, meloxicam, and etodolac, among others.
With the introduction of the selective COX-2 inhibitors, it has been suggested that they may be more cost-effective because of their improved GI tolerability and a reduction in concomitant prescription of anti-ulcer agents.
We will model the length of the spell between diagnosis and initiation of COX-2 inhibitor therapy.
Medicaid paid for COX-2 inhibitor prescriptions for beneficiaries meeting criteria for high GI event risk.
In 2005, these guidelines were amended to include the recommendation that patients with increased cardiovascular risk be cautioned about the risks associated with COX-2 inhibitor use.
In 2005, the AHA issued an advisory after studies suggested that the use of selective COX-2 inhibitors, a type of NSAID, may raise the risk of heart attack and stroke.
Vioxx, a COX-2 inhibitor in anti-inflammatories, was banned in 2004 after it was shown that patients on the drug were more than twice as likely to have heart attacks as those not taking it.
Three studies of COX-2 inhibitors have shown that administration of a COX-2 inhibitor is associated with a reduction in polyps in high-risk patients.
Research has found that the Cox-2 inhibitor celecoxib, which is used to treat arthritis and acute pain, increases by more than twofold the risk of a heart attack.
Don't write off the entire COX-2 inhibitor class of drugs, says Dr.
Meanwhile, COX-2 inhibitor makers received good news in February when a Food and Drug Administration advisory panel concluded that the items' benefits outweighed their risks.
A total of 40, 000 were given another Cox-2 inhibitor, Celebrex, while others were taking ibuprofen or naproxen.