The drugs evaluated by researchers were COX-2 inhibitors
, which include celecoxib, rofecoxib, diclofenac, meloxicam, and etodolac, among others.
We will model the length of the spell between diagnosis and initiation of COX-2 inhibitor
Medicaid paid for COX-2 inhibitor
prescriptions for beneficiaries meeting criteria for high GI event risk.
If further relief is needed, physicians should suggest the least selective COX-2 inhibitors
first, moving progressively toward more selective COX-2 inhibitors
, which are at the bottom of the list, only if needed.
That said, for patients who have an average risk for developing colon cancer--the person with a few polyps, none of which is larger than 1 cm--the current approach of colonoscopy every 3-5 years without a COX-2 inhibitor
is probably the most prudent course.
Patients taking COX-2 inhibitors
may be confused and should speak with
An injectable form of acetaminophen (the active ingredient in Tylenol) and a member of a new class of drugs called COX-2 inhibitors
hold promise as safe and effective tools for controlling surgical pain, according to the American Society of Anesthesiologists.
There's a new classification of drugs on the market called COX-2 inhibitors
that are used to reduce inflammation.
Therefore, restricting cox-2 inhibitor
prescriptions to those written by a rheumatologist is a possibility.
The results from a pre-specified upper gastrointestinal safety analysis of the MEDAL (Multinational Etoricoxib and Diclofenac Arthritis Long-Term) Program comparing the investigational selective COX-2 inhibitor
ARCOXIA([R]) (etoricoxib) and diclofenac, the most widely prescribed non-steroidal anti-inflammatory drug (NSAID) in the world, were published in the February 10, 2007 issue of The Lancet.
A meta-analysis of 91 trials that compared a COX-2 inhibitor
to a non-selective NSAID in patients without cardiovascular disease, demonstrated a similar incidence of serious vascular events in patients taking high-dose (ibuprofen 800 mg 3 times a day, diclofenac 75 mg 2 times a day) non-selective NSAIDs (1.
Two nearly identical trials began in 1999 and 2001 but were stopped in 2004 when more than the expected number of participants developed heart problems while taking the drug, a COX-2 inhibitor
Patients feel betrayed by the COX-2 inhibitor
debate because we dispensed Vioxx or Bextra with the same caution with which we hand out Metamucil packets.
In another study published in Annals of Internal Medicine, the COX-2 inhibitor
rofecoxib was compared to indomethacin, confirming that these drugs reduce kidney function.
Three studies have shown that administration of a COX-2 inhibitor
is associated with a reduction in polyps in high-risk patients.