(5) In our case, partial clonic seizures
started on postnatal second day.
Presentation is with prolonged focal clonic seizures
usually in the setting of a febrile illness, with or without impairment of consciousness.
In the literature, three patients who had recurrent seizures after oral ingestion of 41 mg/kg, 59 mg/kg and 68 mg/kg respectively and patients who had generalized tonic clonic seizures
after oral ingestion of 1-1,5 teaspoon (1 000-1 500 mg) have been reported (8).
We report a case of a 25 year-old man who came into our clinic for a generalized tonic clonic seizure
. He had no history of convulsions in his childhood and his mother didn't have any problems during pregnancy nor did she have delayed labor.
Epilepsy prevalence in Pakistan is 1%.1 Janz described Juvenile Myoclonic Epilepsy (JME) for the first time in 1957.2 Juvenile myoclonic epilepsy (JME) is an idiopathic generalized epileptic syndrome with age related onset.3 The prevalence of JME among other adult and adolescence onset epilepsies is between 4-11%.4 JME begins in the second decade of life with myoclonic jerks (MJ) and in most of patients generalized tonic clonic seizures
(GTCS) are found.
Other generalized seizure types may also occur, including absence seizures and generalized tonic clonic seizures
. Morning jerks often occur and generalized tonic-clonic seizures are often preceded by a series of jerks.
Here, we describe a patient who developed tonic clonic seizures
due to Theophylline toxicity, having ceased smoking 2 weeks earlier.
Other types of generalized seizures are: tonic seizures which involve muscie rigidity but are not followed by a clonic phase; clonic seizures
which involve violent rhythmic contractions but is not preceded by tonic phase; myoclonic seizures in which a person has brief involuntary jerking of the torso or extremities; and atonic seizures in which the skeletal muscles lose all tone causing the person to suddenly drop to the floor.
Patients were ages 15 years or older with a minimal seizure duration of 30 minutes or more or successive generalized tonic clonic seizures
without regaining consciousness in between.
There were no significant differences in latencies to the onset of myoclonic and clonic seizures
and the percentage of the animals showing tonic seizure and death between the water and olive oil groups.
(1) It manifests itself as focal motor clonic seizures
, often persistent for days, weeks, or even years.
Seizures occur as unilateral clonic seizures
repeating frequently or lasting for two hours-two days without interruption and do not recur.
His condition is so severe he has to wear a hard hat to protect him from constant seizures during theday and night, whichcan range from twitches known asmyoclonic jerks to full tonic clonic seizures
, during which his whole body can seize up, leading to potentially dangerous falls and injuries.
Unfortunately, two months later the spasms returned, and evolved into what are now tonic clonic seizures
. I have found some wonderful support through the Lissenceph,qly Network http://www.lissencephaiy.org.