Finally, in medullar region, large chromaffin cells
and numerous blood vessels, similar to that described in Cavia porcellus were found (Kmiec and Kaczmarczyk, 2004).
Although curvature contributions have also been ascribed to phosphatidic acid (PA) in chromaffin cells
(Zeniou-Meyer et al.
Burgoyne RD (1991) Control of exocytosis in adrenal chromaffin cell
The PCI 2 cell line is derived from an induced pheochromocytoma and, when grown in a serum-supplemented medium, PCI 2 cells exhibit many features of their normal counterparts, adrenal chromaffin cells
(Greene and Tischler 1976).
2+] signalling during nerve growth factor-induced neuronal differentiation of rat adrenal chromaffin cells
However, sympathetic paraganglioma are usually secretory neuroendocrine tumors derived from chromaffin cells
Pheochromocytomas arise from the chromaffin cells
of the adrenal gland.
Approximately 85% arise from chromaffin cells
in the adrenal medulla, and 15% arise from chromaffin tissue in extra-adrenal sites extending from the neck to the pelvis, although most are found intra-abdominally.
Cg A, isolated from chromaffin cells
of the adrenal medulla, is an acidic glycoprotein with 439 amino acids (21) and is present in secretory dense core granules located within the cytoplasm of these NE cells (22), However, CgA production seems to depend on tumor type or tumor differentiation and the sensitivity of CgA detection in tissue or plasma may be low in moderately or poorly differentiated NE carcinomas (23).
In the second stage, beginning 48 hours after the injury, the adrenals are greatly enlarged but regain their lipoid granules, while the medullary chromaffin cells
show vacuolization; the edema begins to disappear, numerous basophiles appear in the pituitary; the thyroid shows a tendency towards hyperplasia (more marked in the guinea pig); general body growth ceases, and the gonads become atrophic; in lactating animals, milk secretion stops.
To evaluate the cytotoxic effect in cultured chromaffin cells
, LDH release assay has been used by (Sicard et al.
A primary response is the activation of brain centers, which eventually results in the release of cortisol from the steroid-producing cells and of catecholamines from the head kidney chromaffin cells
Phaeochromocytoma is a catecholamine-secreting, neuroendocrine tumour arising from chromaffin cells
Amperometric recordings in chromaffin cells
from mice exposed to 68 mg (140 [micro]mol)/kg bw BDE-47 did not reveal changes in catecholamine release parameters.
Finite difference time domain (FDTD) simulation played a key role in the development of a unique exposure system that provides online monitoring of non-thermal radio frequency (RF) effects on catecholamine release from cultured adrenal medullary chromaffin cells
, a well-characterized in vitro model of neural-type cells.