Recent research conducted by the United States National Cancer Institute and Cornell University demonstrated that administering reovirus in combination with various chemotherapeutic agents potentiates, or enhances tumour-killing, thus preventing the cancer cells from developing drug resistance," said Dr.
LOS ANGELES -- Chemotherapy during pregnancy may not lead to an elevated rate of fetal malformations if it is given after the first trimester, according to a report on the first 619 cases entered into the federal Registry of Pregnancies Exposed to Chemotherapeutic Agents.
Inovio's Selective Electrochemical Tumor Ablation (SECTA) therapy consists of its MedPulser(R) electroporation device, which significantly enhances local cellular uptake of useful biopharmaceuticals, in conjunction with a designated chemotherapeutic agent and is designed to destroy malignant tissue without harming normal healthy tissue.
The Company recently submitted a clinical protocol for a Phase II study of its lead carbohydrate compound DAVANAT(R) with chemotherapeutic agent 5-FU for first line treatment of patients with cholangiocarcinoma (cancer of the bile duct).
This patent covers methods and compositions for reducing toxicity of a toxic agent in which a polysaccharide (carbohydrate) galactomannan is co-administered with a chemotherapeutic agent in a liquid or powder formulation to reduce toxicity of the agent.