The conclusions of the workshop were that DNA testing for HPV may be added to cervical cytology
for screening in women aged 30 years or more (called primary screening).
An American College of Obstetricians and Gynecologists Technology Assessment on cervical cytology
screening, published in December 2002, mentions the existence of the high-risk HPV DNA test and adds that "it is possible.
Competitive Dialogue in relation to provision of cervical cytology
they have had three consecutive negative cervical cytology
screening test results and have no history of CIN 2 or CIN 3, are not HIV-infected, are not immunocompromised, and were not exposed to diethylstilbestrol in utero or
Second, widespread use of liquid-based preparations (LBPs) for cervical cytology
may affect reporting rates for various descriptive diagnostic categories.
This experience stands in marked contrast to case reports published between 1964 and 2000, in which 21 malignancies were found in 35 women whose cervical cytology
revealed psammoma bodies.
Historically there have been several methods of reporting cervical cytology
Routine screening with HPV testing and cervical cytology
more often than every 3 years for women 30 years and older whose tests were negative at last screening (see 1.
For women with cervical cytology
results showing atypical squamous cell of undetermined significance (ASCUS) and positive results on DNA testing of a cervical sample for human papillomavirus (HPV) high-risk types, about 1 out of 8 progress to cervical intraepithelial neoplasia (CIN) grades 2 or 3 within 2 years of initial colposcopy results showing not more than CIN 1.
With this approval, "you can test for three sexually transmitted diseases and do cervical cytology
on one specimen," commented Dr.
The CINtec(R) In-vitro Diagnostic (IVD) products are based on mtm's technology for the detection of p16INK4a over-expression in biopsies (CINtec(R) p16INK4a Histology) and cervical cytology
specimens (CINtec(R) p16INK4a Cytology).
An analysis of the results of colposcopy, which was performed in 2,609 women found to have atypical squamous cells of undetermined significance (ASCUS) or worse cytology, 5,726 women with a positive HPV test by either of the first-generation HPV DNA assays used in the study (Amplicor HPV test and Linear Array HPG genotyping), and 1,041 women who were HPV negative and who had negative for intraepithelial or malignant (NILM) cervical cytology
, showed that the cobas HPV test was significantly more sensitive for detecting CIN 3 or worse than was liquid-based cytology at a threshold of ASCUS or worse (92% vs.
Used adjunctively with the Cervista[TM] HPV HR test in patients with ASC-US cervical cytology
results, to assess the presence or absence of specific high-risk HPV types.
We gathered medical record data by using a retrospective review of medical records, including the medical record number, date of birth, date of service, provider performing pelvic examination or obtaining cervical cytology
smear, identification of the laboratory processing and reporting each cytology report, and insurance coverage (Medicare, private, self-payer, and TennCare/ Medicaid).
This simply requires that a portion of the cervical cytology
specimen be retained in case HPV testing should be needed following the initial screening.