sensitization

(redirected from Central sensitization)
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Synonyms for sensitization

the state of being sensitive (as to an antigen)

(psychology) the process of becoming highly sensitive to specific events or situations (especially emotional events or situations)

rendering an organism sensitive to a serum by a series of injections

References in periodicals archive ?
32] suggested that central sensitization in knee OA is apparent among patients with high levels of pain in the absence of moderate-to-severe radiographic evidence of knee OA.
On the other hand, TMD can be considered a potential perpetuating factor for migraine because it acts as a constant nociceptive input that contributes to maintaining central sensitization and abnormal pain processes.
In 2012 Titani was exposed to unsafe level of volatile organic compounds and a melange of particulates, fumes, dust, and unidentified stuff in her workplace, and since then has researched her resulting asthma, central sensitization, and three central sensitivity syndromes--multiple chemical sensitivities, irritable larynx syndrome, and chronic fatigue syndrome--and sharing the information with others who may suffer from the same conditions.
The central sensitization theory may explain these links.
But as the pain becomes chronic, an overlap of multiple mechanisms develops, with central sensitization often playing a more dominant role than peripheral stimulation (regardless of the diagnosis).
Chronic pain conditions involve many peripheral and central sensitization processes, from nerve endings to the brain's perception of pain.
Collectively, findings from different sources of research suggest that peripheral tissue or nerve injury may induce central sensitization, which is associated with spinal changes that may contribute to the development of MDs.
Nijs J, Paul van Wilgen C, Van Oosterwijck J, van Ittersum M, Meeus M (2011) How to explain central sensitization to patients with 'unexplained' chronic musculoskeletal pain: Practice guidelines.
The more vexing problem in managing rheumatologic disorders involves patients with central sensitization and chronic pain.
The power of the central sensitization analogy the idea that pain is best thought about as a stereo with the volume turned up--has led to the science of fibromyalgia becoming "lost in translation," according to Dr.
However, through this important case report and future research, we hypothesise that failure to fully resect these lesions at the time of TKR surgery or the development of new BMLs within the subchondral bone after TKR surgery may act as a continued peripheral nociceptive input, maintaining pain, altered central processing, and central sensitization after TKR.
Treatment of Myofascial pain syndrome is difficult because it may be initiated by peripheral and central mechanisms that appear to be inter-related as Central sensitization would lead to an increased excitability of spinal and supraspinal regions resulting from injury or inflammation-induced activation of peripheral nociceptors.
Findings published in Arthritis Care and Research, a journal of the American College of Rheumatology (ACR), further show OA patients who catastrophize"consumed by thoughts of pain"had increased central sensitization that was associated with greater clinical pain.
TEHRAN (FNA)- Sleep disruption appears to be associated with altered pain processing and central sensitization, according to research.
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