programmed cell death

(redirected from Cellular aging)
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Synonyms for programmed cell death

a type of cell death in which the cell uses specialized cellular machinery to kill itself

References in periodicals archive ?
Scientists Discover Novel Way to Reset Cellular Aging Clock
RELATED ARTICLE: PQQ: Powerful Protection Against Cellular Aging
Based on that, the researchers propose that higher levels of anticipated threat in daily life may promote cellular aging in chronically stressed individuals.
Using precise genetic modifications, normal human cells were induced to reverse both the 'clock' of differentiation (the process by which an embryonic stem cell becomes the many specialized differentiated cell types of the body), and the 'clock' of cellular aging (telomere length).
Editor's note: Telomeres cap and protect the ends of chromosomes and shorten with the passage of time, which makes them useful as a marker of cellular aging.
These toxins may alter the cell's DNA and thereby the activity of genes, resulting in cellular aging.
BioTime scientists and their collaborators show in this paper that many iPS cell lines currently being circulated in the scientific community have short telomeres, meaning that their clock of cellular aging is still set at the age of relatively old cells.
The functions and properties of mitochondria might render subsets of selectively vulnerable neurons intrinsically susceptible to cellular aging and stress and overlying genetic variations, triggering neurodegeneration according to a cell death matrix theory.
Cellular aging remains somewhat of a mystery, although there is growing evidence that over time, the DNA within cells begins to show signs of aging.
The article states that iPS cells show abnormal expansion and early cellular aging, raising important questions about the future prospects for iPS cell-based therapies and supporting the use of ACT's embryo-safe single blastomere-derived human embryonic stem cell lines, which do not exhibit these problems.
Whereas the study published in 2010 intentionally used older, viral-based means of introducing genes, BioTime now plans further studies of cellular aging reversal using its proprietary ReCyte[TM] technology specifically designed to rapidly reprogram cells in a manner expected to prevent the telomeric and other genetic abnormalities afflicting previous iPS cell approaches.
Washington, Nov 21 (ANI): Kids, who suffer physical or emotional abuse, are more likely to undergo accelerated cellular aging as adults, according to new research from Butler Hospital and Brown University.
The paper reports that iPS cells exhibit abnormal expansion and early cellular aging, raising important questions about the future prospects for iPS cell-based therapies and supporting the use of ACT's embryo-safe single blastomere-derived human embryonic stem cell lines, which do not exhibit these problems.
You will also discover its potential to reverse cellular aging by activating genes that induce mitochondrial biogenesis--the spontaneous formation of new mitochondria in aging cells
They later identified the human counterpart, a discovery that could be beneficial in understanding human cancers and cellular aging.
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