active site

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Related to Catalytic site: active site, induced fit model
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  • noun

Words related to active site

the part of an enzyme or antibody where the chemical reaction occurs

References in periodicals archive ?
Since the catalytic site is localized in the [beta] subunit, intrinsic property of [beta] monomer would be important to understand the rotational catalysis of [F.
It is the central region where the active catalytic site of the enzyme is present and is composed of a number of motifs that are conserved throughout evolution in very distant related proteins.
In the new research, the scientists investigated the catalytic site of photosystem II, referred to as the oxygen-evolving complex.
2+] ions in the catalytic site, in the presence of viral DNA only one would be available to interact with one incoming inhibitor molecule, because the second ion may be largely shielded, while the first ion could be much more exposed (37).
the catalytic sites of enzymes displaying specificities not obtainable with antibodies from commonly used laboratory animals (13).
The amino acid alignments of catalytic sites of the related PLBs is shown in Fig.
A molecular docking study was used to determine the free binding energy and binding simulations of the tanshinones on the binding to the catalytic site on CYP2D6, which could be helpful for the understanding of the interaction between the tanshinones and human CYP2D6.
Peptidase activity, however, is retained when peptide substrates with molecular weights <8000 are used because they are still able to reach the catalytic site.
NCINIs inhibit HIV integrase by binding to a novel site, distinct from the catalytic site used by the current class of integrase inhibitors, and therefore may possess a differentiated resistance profile from raltegravir or elvitegravir.
GRN163L is a short chain oligonucleotide that binds with high affinity and specificity to the catalytic site of telomerase, resulting in competitive inhibition of enzyme activity.
As demonstrated by the applicant in preliminary work, a suitable IL layer strongly influences the active catalytic site in a very promising manner, apparently via a highly complex interplay of solvent-, ligand- and electrostatic-stabilization effects.
GRN163L is a short chain oligonucleotide that binds with very high affinity and specificity to the catalytic site of telomerase, resulting in competitive inhibition of enzyme activity.
He plans to use a binding assay to select from the mixture the best candidate for the binding site or catalytic site desired.
GRN163L binds directly with high affinity to the template region of the RNA component of human telomerase (hTR), which lies in the active or catalytic site of hTERT, the telomerase reverse transcriptase.