Stallworth et al., "HL-1 cells: A cardiac muscle cell
line that contracts and retains phenotypic characteristics of the adult cardiomyocyte," Proceedings of the National Academy of Sciences of the United States of America, vol.
Grafts of human cardiac muscle cells
, grown from embryonic stem cells, coupled electrically and contracted synchronously with host muscle following transplantation in guinea pig hearts.
Taken together, the results identify the cardionogen family members as important modulators of cardiac muscle cell
"If you want to know how drugs such as beta blockers work in the adult heart, it's better to test those in more mature, human iPSC-derived cardiac muscle cells
," said Kamp.
Washington (USA) Dec 20 ( ANI ): A faster, more cost-efficient, and more accurate method of examining the effectiveness of human pluripotent stem-cell-derived cardiac muscle cells
has been discovered, according to a new study.
Thomas Scheibel, a professor of biomaterials at the University of Bayreuth's Department of Engineering, is working on a project to show how spider silk could be used to help restore cardiac muscle cells
lost in a heart attack.
The main cause lies in irreversible loss of cardiac muscle cells
due to disease, especially ischemic diseases like cardiac infarction.
Growth and Hyperplasia of Cardiac Muscle Cells
. London: Harwood Academic Publishers; 1991.
In turn, this enables us to study the effects of experimentally induced type 1 and type 2 diabetes on calcium signalling in individual cardiac muscle cells
The innovative cardiac muscle assay developed by the team here at Domainex working in partnership with Imperial College London, is enabling early testing on human cardiac muscle cells
, which will make cardiac drug discovery more efficient and effective in identifying efficacious candidate drugs.'
However, these cells are readily recognizable as cardiac muscle cells
by their characteristic cytoplasmic features including prominent eosinophilia and cross-striation.
*An impulse-conducting system of the heart for initiation and propagation of electrical impulses for cardiac muscle contraction It is formed by highly specialized cardiac muscle cells
(Purkinje fibers), which generate and conduct electrical impulses rapidly through the heart.
HCM is a primary disorder of the cardiac muscle cells
, which are enlarged and arranged in a disorganized fashion.
But embryonic cardiomyocytes (cardiac muscle cells
) can multiply, with embryonic stem cells providing an endless reservoir for new cardiac tissue.
They are released into the circulation when damage to cardiac muscle cells