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Patients with high hematocrit values had late onset hypotension and capillary leak syndrome.
Capillary leak syndrome was noted among 3 patients and 1 of them had moderate to severe renal failure also.
The systemic capillary leak syndrome (SCLS) is characterized by spontaneous recurrent episodes of hypotension, haemoconcentration, generalized oedema, and in most cases, the presence of a paraprotein.
A capillary leak syndrome was considered on the basis of severe hypovolaemic shock, oedema, haemoconcentration, and low albumin level.
Capillary leak syndrome resulting in death has been reported.
Capillary leak syndrome - Capillary leak syndrome is the occurrence of at least 2 of the following 3 symptoms (low blood pressure, edema, low blood albumin) at any time during ONTAK therapy.
Capillary leak syndrome in a 5-month-old infant associated with intractable diarrhoea.
tachypnea, tachycardia, hypotension, pulmonary edema) that could develop into systemic inflammatory response syndrome (SIRS), capillary leak syndrome, or organ dysfunction.
Proleukin can result in a number of adverse events including capillary leak syndrome (CLS) and flu-like symptoms.