In CPPD, ultrasound was useful in identifying calcium pyrophosphate
crystals via specific anatomic characteristics of the crystals and provided a radiation-free alternative to the conventional X-ray.
crystal formation is principally dependent on the presence of extracellular inorganic pyrophosphate (PPi) mostly produced in the joints by chondrocytes.
Our patient may have been predisposed to septic arthritis by the intracellular calcium pyrophosphate
crystals found in his synovial fluid as well as his history of osteoarthritis and gout, although we could not find evidence of a definitive diagnosis of gout in the past.
The rare concurrent diagnoses included (1) forearm/hand compartment syndrome, (2) calcium pyrophosphate
crystals (pseudogout) in the wrist, (3) monosodium urate crystals, gouty tophi, and S.
Unlike in gout, there is currently no effective treatment that reduces or removes calcium pyrophosphate
crystals from a joint.
KEY WORDS: chiropractic, ankle, calcium pyrophosphate
Rada, "Pseudogout-associated inflammatory calcium pyrophosphate
dihydrate microcrystals induce formation of neutrophil extracellular traps," Journal of Immunology, vol.
The study's results showed that ultrasound provided excellent specificity for gout in the setting of acute calcium pyrophosphate
deposition disease (CPPD), also known as pseudogout, particularly in distinguish ing the deposition of monosodium urate on the surface of cartilage (double contour sign), and calcium pyrophosphate
within the matrix of the cartilage (interface sign).
He also discussed about calcium pyrophosphate
disease, Takayasu arteritis, Sjogren syndrome which increases the risk of developing lymphoma.
(2,3,9) Other crystal deposition diseases, which include gout (monosodium urate) and pseudogout (calcium pyrophosphate
dihydrate), are similar to acute calcific longus colli tendonitis in that they all deposit a crystalline substance into the soft tissues.
Researchers at Tehran (Iran) University of Medical Sciences randomized 61 postmenopausal women with moderate to severe knee osteoarthritis (OA) and no evidence of calcium pyrophosphate
deposition disease on x-ray to 0.5 mg twice daily of colchicine or placebo in a double-blind clinical trial.
These breakthroughs in the field of gout have given a new insight into other crystal-induced arthropathies  and recent international guidelines have been produced for both the treatment of gout [4, 5] and calcium pyrophosphate
deposition (CPPD) .
Pseudogout is a real condition, although it's often called acute calcium pyrophosphate
Pseudo gout is caused by deposits of calcium pyrophosphate
crystals within the affected joints--usually the knee, wrist or shoulder.