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References in periodicals archive ?
The finding that Cajal cells express c-kit (CD117), a tyrosine kinase, is a considerable development.
Ten large magnification areas were counted in the same specimen from each case, and the number of Cajal cells was quantitatively determined.
It was determined that the Cajal cells were encountered more frequently in the control group.
This hypothesis is based in the ultrastructural similarities of GIST and Cajal cells. Both types of cells express the CD 117 protein, but Cajal cells do not stain for CD 34 nor for other muscle cell antigens frequently seen in GIST cells.
Cajal cells are located in the muscle layer of the gastrointestinal tract as the pacemaker cells of the gastrointestinal tract and commonly express c-kit proteins (CD117), myeloid stem cell antigen (CD34), and vimentin.