CONCLUSIONS: The present study shows that AIDS related ophthalmic manifestations are significant ophthalmic problem and the anterior segment involvement is common with herpes zoster virus and the posterior segment involvement is commonly associated with CMV retinitis
correlating with CD4 and CD8 counts.
7, an advisory panel of independent scientists cut the trial short after its review showed that AIDS patients taking foscarnet lived an average of 12 months after developing CMV retinitis
, while those on ganciclovir survived for an average of eight months.
Disease <50 150 250 1 Tuberculosis 20 36 40 2 Oral 6 26 20 Candidiasis 3 Chronic 0 12 6 Diarrhea 4 Pneumonia 0 8 4 5 Herpes Zoster 0 0 4 6 CMV Retinitis
2 0 0 7 Pneumocystis 0 2 0 jirovecii pneumonia(PCP) The Relationship Between CD4 Count Level and Type of Tuberculosis 1 Pulmonary 20 26 16 TB (PTB) Pleural 0 0 6 effusion 2 Extra TB 0 4 12 Lymphadenopathy Pulmonary TB Abdomen 0 2 4 Meningitis 0 4 2 CD4 Count Sl.
(1) We present a patient with HIV/AIDS who was profoundly immunecompromised when she presented with CMV retinitis
. At that time, a contrast-enhanced CT scan showed that her brain (and medium-sized cerebral vessels) were normal, apart from HIV-associated cortical atrophy.
This characterization may lead ophthalmologists to misdiagnose CMV retinitis
in patients who seem otherwise healthy.
Therapy for CMV retinitis
consists of oral valganciclovir, I/V ganciclovir, or I/V Foscarnet with cidofovir as alternative.
Valganciclovir can be used in the oral form to initiate and maintain CMV treatment in HIV CMV retinitis
Although the true incidence of CMV retinitis
in non-human immunodeficiency virus (HIV) population such as leukemia is unknown [1, 2], but its occurrence is considered very rare especially in those with pediatric acute myeloid leukemia (AML) in the nontransplant setting .
Common ocular manifestations in combined immunodeficiency include CMV retinitis
followed by chorioretinitis and optic neuritis .
Fundoscopy did not reveal CMV retinitis
. He had normocytic normochromic anaemia (Hb: 10.7 g/dl), normal total leucocyte, and differential counts.
[3,4] Prior to the introduction of ART) 30-40% of HIV-infected individuals developed CMV retinitis
.  However, the introduction of ART has resulted in a precipitous decline in CMV retinitis
infections, which is particularly evident in the developed world.
Survival analysis was performed using Cox backward stepwise regression analysis with the variables associated or near association (less than eight years of education, less than 200 cells/mm3 of CD4 at failure, CMV retinitis
or CNS toxoplasmosis, presence of comorbidities), prediction of death between groups (with or without a diagnosis of TB).
 CMV retinitis
is known to occur in immunocompromised adults, affecting up to 30% of HIV-positive adults and 5% of immunocompromised children.
Four patients were initiated to ART following diagnosis of ocular lesions, three patients for CMV retinitis
and one for Toxoplasma retinochoroiditis.
Indications include treatment of patients with CMV retinitis
, a major cause of blindness in immunocompromised patients (especially patients with advanced AIDS).