Whether a panel test or more-comprehensive testing methods are used, the inclusion in CF tests
of mutations that are disproportionately present in nonwhite, non-Ashkenazi Jewish ethnicities would be expected to produce better diagnostic sensitivities in these and mixed populations.
Thus, the rates of CF responding were similar during the analogue CF test
and the CF replication test.
The protocol for the xTAG Cystic Fibrosis 39 Kit v2 has been streamlined to make the test fast and easy to use, with less hands-on time for laboratory technicians than any other CF test
The antigen used in the CF tests
was prepared from brains of infected baby mice injected intracerebrally with vaccinia virus; infected brains were treated by the sucrose acetone extraction method (4).
Forward-Looking Statements Except for the historical information contained herein, the matters set forth in this press release, including statements regarding the expected benefits, impact, and value of the Heredi-T (TM) CF test
to healthcare providers and their patients, the Company's commitment to improving healthcare through revolutionary genetic analysis solutions, and Sequenom CMM's impact on the landscape in genetic diagnostics, are forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995.
Reagents for the CF test
were supplied by the Onderstepoort Veterinary Institute, South Africa, and the Centers for Disease Control and Prevention, Division of Vector-Borne Infectious Diseases, Fort Collins, Colorado.
In CF tests
, CT-114 HMAF reacted with five vesicular stomatitis serogroup antigens: Chandipura, Isfahan, Maraba, Jurona, and La Joya (Table 2).
Serologic examination of domestic animals by CF test
gave [ILLEGIBLE TEXT] results for goats (26% of 969) and sheep (28% of 421).
CLIA-certified SeqWright is a leader in the field of contract genomics and provided the FDA-level genotyping that ultimately validated the InPlex(TM) CF test
by demonstrating it had 99.
In addition, Asuragen will develop, also for Digene's exclusive distribution, the next generation CF test
, Signature CF Expand, which expands the mutation panel to include ethnic-specific mutations that can be adapted for use in carrier screening and may find additional utility for neonatal and newborn testing.
Having the CE Mark on our Tag-It(TM) CF test
expands our reach into the European market for CF testing and further asserts our leadership position in the clinical genetic testing market," said Greg Hines, President and CEO of Tm Bioscience.
Accurate interpretation of CF test
results, most especially negative results, requires careful interpretation of complex data.
Having the first CF test
and second multiplexed genetic test behind Roche's (RHHBF.