CD8 cell

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Related to CD8+ cell: Cytotoxic T lymphocytes
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  • noun

Synonyms for CD8 cell

T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it

References in periodicals archive ?
Immune subsets were defined using the following markers: naive CD4+ T-cells defined by CD4+, CD45RA+, and CD62L+; memory CD4+ T-cells defined by CD4+, CD45RO+, and CD45RA-; functional CD4+ T-cells defined by CD28+ and CD4+; activated CD8+ cells defined by CD8+, CD38+, or HLA-DR+.
CD4/CD8 ratio CD8+ cells Study groups (Mean [+ or -] SD) (Mean [+ or -] SD) Pulmonary 1.
When combined with viral load data, CD4+ and CD8+ cell counts also indicate disease progression, response to therapy and development of resistance.
Data from the literature report that the expression of CD4+ and CD8+ cells is similar in the paucibacillary (tuberculoid) and multibacillary (histoid) forms (10).
After the treatment the number of CD8+ cells decreased more than 2 times.
It inhibits cytokine production in Th1 and CD8+ cells, but not in Th2 cells.
A protein produced by CD8+ cells of the adaptive immune system is exerting potent viral-suppressive activity through a mechanism thought to be reserved for cells of the innate immune system," said a co-author of the study.
CD8+ lymphocyte activation at human immunodeficiency virus type 1 seroconversion: development of HLA-DR+ CD38- CD8+ cells is associated with subsequent stable CD4+ cell levels.
We and the others (34,35) have shown that the lesions of SCC are infiltrated with higher CD4+ and CD8+ cells when compared to CIN III, HPV positive cervicitis and normal cervix.
This association of phenotype and function is not absolute, since CD4+ cells may exhibit lytic activity, while CD8+ cells secrete antiviral cytokines, notably interferon-[gamma] (IFN-[gamma]) and tumor necrosis factor.
Synovial fluid analyses from psoriatic arthritis patients have shown a reduction in CD4+ and CD8+ cells from baseline following treatment with alefacept.