cytotoxic T cell

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Related to CD8+ T cells: lymphocyte activation
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Synonyms for cytotoxic T cell

T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it

References in periodicals archive ?
Published evidence underlines the future potential of CD8+ T cells for distinguishing active from latent TB, discerning recent vs.
To see if attracting CD8+ T cells into tumors helped surmount this obstacle, the researchers treated 21 patients with advanced melanoma with pembrolizumab and T-vec, an intratumorally administered, genetically modified clinical herpes simplex virus-1 strain approved for treating melanoma.
These CD8+ T cells have been shown to play an important role in Mycobacterium tuberculosis immunity, concluded the company.
CD8+ T cells recognize and kill cancer cells and an increased presence of intra-tumoral CD8+ T cells may result in improved prognosis and survival in patients.
This paper sheds light on the markers of activation and inflammation in CD8+ T cells and the Interferon-1 pathway which helps stimulate their function.
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.
It is well-established that patients with autoimmune disease have decreased levels of CD8+ T cells and an elevated CD4/CD8 ratio.
Activation and cell cycle antigens in CD4+ and CD8+ T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection.
The CD4+ T cells count and percentage, the CD8+ T cells count and the CD4+ T cells/CD8+ T cells of them ratio improvement are shown in table 1 and figure 2: A-D.
Expression of inhibitory receptors on CD4+ and CD8+ t cells from healthy Colombian donors
CD8+ T cells ("killer T cells"), on the other hand, normally attack and destroy only infected cells.
The most established marker of immune activation in HIV-1 infection is the expression of CD38 on CD8+ T cells.
Researchers have discovered that prostate tumors in mice can cause immune cells known as CD8+ T cells to change their function from cells that have antitumor activity to cells that suppress immune responses.