CD4 T cell


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Synonyms for CD4 T cell

T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells

References in periodicals archive ?
Restoration of the CD4 T cell compartment after long-term highly active antiretroviral therapy without phenotypical signs of accelerated immunological aging.
CD4 T cells: balancing the coming and going of autoimmune-mediated inflammation in the CNS.
CD4 T cell measurements in the management of antiretroviral therapy--A review with an emphasis on pediatric HIV-infected patients.
The modern ART of HIV infection management: Towards a tailored approach to maximize CD4 T cell reconstitution.
Biopsy samples obtained from the gut and respiratory mucosa during chronic infection demonstrated profound mucosal CD4 T cell depletion in all SIV-infected animals, at levels similar to those described in the context of HIV infection.
STI duration and design are discrepant: in particular, the triggers for re-initiating therapy (predetermined schedule, viral load rebound, or drop in CD4 T cell count).
(3) These data help explain why patients on treatment (particularly those "salvage" patients who are heavily treatment experienced with several drug-resistance mutations), no matter how high the viral load or low the CD4 T cell count, appear to do better clinically than patients who are off treatment.
These monkeys also maintained their CD4 T cell counts, the scientists report in the Oct.
While the incidence of ARL in HIV infection has decreased overall since the advent of HAART, there has been no change within any patient grouping defined by CD4 T cell counts.
OI occurred only when both IFN-[alpha] generation and CD4 T cell counts were sufficiently depressed.
In addition, animals given the Ad5 vaccine have shown stable CD4 T cell levels and viral control out to 2 years after SHIV challenge (see Figure).
Specifically, investigators are usually interested in changes in the CD4 T cell count or viral load or both.
Results from large studies showed that CD4 T cell count correlated with risk of HIV disease progression--the lower the count, the more likely someone was to develop a severe life-threatening disease or die.
CD4 T cell count was 410 cells/[mm.sup.3] and CD8 T cell count was 940 cells/[mm.sup.3].
Of 3 determinations, her average CD4 T cell count has been 489 cells/[mm.sup.3]; average viral load, 17,500 copies/mL.