The weekly and monthly CAM2038 injectable
buprenorphine products have been evaluated, thus far, in 176 healthy volunteers and patients in three shorter-term clinical trials demonstrating a promising drug release, safety, and tolerability profile.
As an in-office prescription,
buprenorphine is easier to access than methadone, and a large, randomized trial that pitted methadone against
buprenorphine found that women treated with
buprenorphine have fewer delivery complications (N EnglJ Med.
NASDAQ: BDSI) today presented data from a Phase 2 study for the investigational drug
buprenorphine HCl buccal film utilizing BDSI's patented BioErodible MucoAdhesive (BEMA[sup.
The ISTART Trial (n=758) was a randomized, non-inferiority, multicenter study to assess early treatment efficacy when switching between treatments of ZUBSOLV in comparison to generic
buprenorphine monotherapy for induction and Suboxone Film of opioid maintenance therapy.
Medicaid, a health entitlement program jointly funded by states and the federal government, funds a significant proportion of
buprenorphine treatment in the United States (Ducharme and Abraham 2008; Stein et al.
Plasma
buprenorphine concentrations were measured by use of tandem liquid chromatographymass spectrometry.
Being in a state where Medicaid was reimbursing for
buprenorphine [made a positive difference], and also some states devoted some of their block grant funding to support the use of
buprenorphine, so the counties in those states were associated with having substantially more doctors.
As previously announced an additional co-primary endpoint assessed Zubsolv as a treatment for induction of
buprenorphine maintenance therapy compared to generic
buprenorphine monotherapy.
For one thing, extremely low concentrations of
buprenorphine applied in a patch means that the overall amounts of
buprenorphine excreted into urine would be much lower, not to mention only one third of the
buprenorphine dose is eliminated through the urinary route and the other two thirds by feces.
Amneal Pharmaceuticals
buprenorphine HCl and naloxone HCl tablets in 2 mg/0.
In April 2008, only 10 months and 29 admissions into our venture into
buprenorphine treatment, we closed the door to new admissions.
Previous retrospective studies showed that
buprenorphine was more effective than tramadol for acute heroin withdrawal, Dr.
Numerous studies support the efficacy of opiate agonist treatment with either methadone or
buprenorphine (Fudala et al.
Babies born to women addicted to opioids fare better when their mothers are treated with either the addiction medication
buprenorphine or methadone than babies whose mothers are not treated at all.
The medication
buprenorphine implanted under the skin and released over months can ease drug cravings and helps some patients stay clean, researchers report in the Oct.