Association of objectively measured physical activity with brown adipose tissue
volume and activity in young adults.
Dietary calcium supplementation in adult rats reverts brown adipose tissue
dysfunction programmed by postnatal early overfeeding.
The study demonstrated a direct relationship between the metabolic activation of the brown adipose tissue
measured using hemoglobin gradients as an intrinsic biomarker of tissue metabolism and its calorie consumption after stimulation.
Matsushita et al., "Recruited brown adipose tissue
as an antiobesity agent in humans," Journal of Clinical Investigation, vol.
Enerback, "Brown Adipose Tissue
In Humans: A New Target for Anti-Obesity Therapy," in Novel Insights into Adipose Cell Functions, Research and Perspectives in Endocrine Interactions, pp.
Kobayashi, "Thyroid-stimulating hormone receptor in brown adipose tissue
is involved in the regulation of thermogenesis," American Journal of Physiology-Endocrinology and Metabolism, vol.
In contrast, brown adipose tissue
is important for both basal and thermal energy expenditure .
Therefore, the adipose organ comprises white adipose tissue (WAT), the main energy storage allowing animals to survive for longer periods without meals, and brown adipose tissue
(BAT), a key site of heat production (thermogenesis) in mammals, essential for the survival in cold environments and in hibernators, defending core body temperature.
Thermogenesis, fatty acid synthesis with oxidation, and inflammation in the brown adipose tissue
of ob/ob (-/-) mice.
The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue
. Journal of Clinical Investigation 108(9): 1379-1385, 2001.
Cold can induce an increase in mitochondrial protein contents and COX activity both in liver and brown adipose tissue
, suggesting that A.
UCP-1 is highly expressed in brown adipose tissue
 in a PGC-1-dependent manner to increase energy expenditure and oxygen consumption .
Transformation of white adipose tissue into beige or brown adipose tissue
, a process recently named "browning" [50-53], might be triggered by systemic inflammation.
Brown adipose tissue
(BAT) is a key regulator in energy balance, protecting infants from hypothermia and a major contributor to diet-induced thermogenesis .
There are two types of adipose tissue, white adipose tissue and brown adipose tissue
. The excess energy was mainly stored in the white adipose tissue in the form of triglycerides (TAGs).