Researchers concluded calcium administered during pregnancy and the early postpartum period, to women with intakes around adequacy, was associated with reduced bone resorption
and, thus, may constitute a practical intervention to prevent transient skeletal loss associated with childbearing.
Sitton Professor of the Department of Nutrition, Food and Exercise Sciences and Director of the Center for Advancing Exercise and Nutrition Research on Aging (CAENRA) in the College of Human Sciences, was due, in part, to the ability of dried plums to suppress the rate of bone resorption
, or the breakdown of bone, which tends to exceed the rate of new bone growth as people age.
Unlike both dentures and bridge-supported crowns, dental implants prevent bone resorption
and are more comfortable and natural looking.
The finite element model for bone resorption
was shown in Figure 2.
2011) with two studies of young males and females reporting increased bone formation markers but no changes in markers of bone resorption
after 8 weeks of training.
Biochemical markers of bone resorption
have been used to characterize metabolic bone diseases and assess therapeutic response in postmenopausal women .
CTX is significantly lower in mice fed with Peptan(TM) indicating that bone resorption
6) Bone resorption
was decreased, when compared to milk protein.
Reports from two phase II studies of denosumab for treating patients with bone metastases from solid tumors showed that the drug was at least as effective as an intravenous bisphosphonate for reducing a plasma marker of bone resorption
Preclinical and Phase 1 studies have shown that Ostabolin-C stimulates significant bone formation with little to no stimulation of bone resorption
There are also some data suggesting that the hormone leptin, which is involved in regulating body weight and appetite, increases bone resorption
(the process of losing bone).
It is interesting that this section begins with a description of bone formation markers, whereas we have already learned that the bone remodeling cycle begins with bone resorption
and the most widely prescribed therapies act by inhibiting bone resorption
BSAP reflects bone formation, while DPD reflects bone resorption
When women reach menopause, bone resorption
significantly exceeds formation; the activity of the osteoblasts cannot keep up with the activity of the osteoclasts, and women begin to lose bone more rapidly.
Although there are drugs that prevent bone resorption
by osteoclasts, only one Food and Drug Administration-approved compound, parathyroid hormone, stimulates bone formation.