The possibility of bone marrow suppression
due to the disease itself has to be considered in patients with LL presenting with pancytopenia.
Drug-induced thrombocytopenia is the result of bone marrow suppression
and destruction of platelets in peripheral blood due to immune or non-immune mechanisms (1), (2).
Hematological side effects of clopidogrel has been known for a long time and bone marrow suppression
has been reported in case reports.
My dog was diagnosed in the middle of September with immune mediated bone marrow suppression
, brought on by Phenobarbital use.
Cancer treatment regularly causes bleeding, since almost all chemotherapy agents cause bone marrow suppression
, and therefore thrombocytopenia, but bleeding is also secondary to DIC in a few cases.
"If you're going to give it for a prolonged period of time, you need to watch the complete blood count because linezolid can cause bone marrow suppression
Previous reticulocyte maturity studies show the usefulness of IRF in the monitoring of bone marrow suppression
post chemotherapy, monitoring of bone marrow engraftment post transplantation, classification of anaemia, and monitoring of erythropoiesis (1, 4-6).
Clinical signs vary from intermittent fever, lymph node enlargement, kidney and retinal haemorrhage, weight loss and eye problems to bone marrow suppression
Unfortunately, as Lassen (a colleague of Bjorn Ibsen's) and colleagues reported in 1956, prolonged use of nitrous oxide could cause bone marrow suppression
, and even fatal aplastic anemia.
In addition, it may cause bone marrow suppression
and lung disease.
Carbamazepine is particularly effective in patients who haven't responded to other medications; however, the risk of serious bone marrow suppression
with this anticonvulsant dictates very close patient monitoring.
The privately held company develops anti-cancer therapies, treatments for chemotherapy-related bone marrow suppression
and drugs to manage transplant rejection.
Although no lasting adverse effect related to use of the drug occurred, treatment with chloramphenicol was discontinued for two patients because of chloramphenicol-induced bone marrow suppression
The British National Formulary (BNF), which provides guidelines on medication for GPs, states: 'Doctors are reminded of the importance of recognising bone marrow suppression
induced by carbimazole and the need to stop treatment promptly.