The possibility of
bone marrow suppression due to the disease itself has to be considered in patients with LL presenting with pancytopenia.
Drug-induced thrombocytopenia is the result of
bone marrow suppression and destruction of platelets in peripheral blood due to immune or non-immune mechanisms (1), (2).
Hematological side effects of clopidogrel has been known for a long time and
bone marrow suppression has been reported in case reports.
My dog was diagnosed in the middle of September with immune mediated
bone marrow suppression, brought on by Phenobarbital use.
Cancer treatment regularly causes bleeding, since almost all chemotherapy agents cause
bone marrow suppression, and therefore thrombocytopenia, but bleeding is also secondary to DIC in a few cases.
"If you're going to give it for a prolonged period of time, you need to watch the complete blood count because linezolid can cause
bone marrow suppression," Dr.
Previous reticulocyte maturity studies show the usefulness of IRF in the monitoring of
bone marrow suppression post chemotherapy, monitoring of bone marrow engraftment post transplantation, classification of anaemia, and monitoring of erythropoiesis (1, 4-6).
Clinical signs vary from intermittent fever, lymph node enlargement, kidney and retinal haemorrhage, weight loss and eye problems to
bone marrow suppression.
Unfortunately, as Lassen (a colleague of Bjorn Ibsen's) and colleagues reported in 1956, prolonged use of nitrous oxide could cause
bone marrow suppression, and even fatal aplastic anemia.
In addition, it may cause
bone marrow suppression and lung disease.
Carbamazepine is particularly effective in patients who haven't responded to other medications; however, the risk of serious
bone marrow suppression with this anticonvulsant dictates very close patient monitoring.
The privately held company develops anti-cancer therapies, treatments for chemotherapy-related
bone marrow suppression and drugs to manage transplant rejection.
Although no lasting adverse effect related to use of the drug occurred, treatment with chloramphenicol was discontinued for two patients because of chloramphenicol-induced
bone marrow suppression (43).
The British National Formulary (BNF), which provides guidelines on medication for GPs, states: 'Doctors are reminded of the importance of recognising
bone marrow suppression induced by carbimazole and the need to stop treatment promptly.
