The mice bone marrow cell
micronucleus test is a sensitive indicator for study of the genetic toxicity induced by xenobiotics.
The objective of the present study, therefore was to analyse the cytogenetic ramifications of HTP using in vivo SWR/J mouse bone marrow cells
Understanding how the protein HMGB1 works as a distress signal to summon these bone marrow cells
is expected to have significant implications for clinical medicine, and could potentially revolutionise the management of wound healing.
If confirmed, the research might also help scientists find a way to prevent bone marrow cells
from invading or to identify markers that would allow an earlier diagnosis for Barrett's esophagus, which is usually asymptomatic.
Allogeneic mesenchymal bone marrow cells
are obtained from donors by extracting bone marrow and are expanded at Stemedica's cGMP compliant facility, which is licensed by the California Department of Public Health, Food and Drug Branch.
A small study in the Netherlands, published in the May 20 issue of Journal of the American Medical Association, found that bone marrow cells
injected into the heart may improve myocardial perfusion (flow of blood in the heart) in patients with chronic myocardial ischemia--a painful condition resulting from a temporary lack of oxygen-rich blood flow to the heart.
Thus, FIV infection of bone marrow cells
contributes to the production of the immunodeficient state as well as other blood abnormalities in infected cats.
Although tumors are known to generate proteins that do the job, researchers have recently implicated bone marrow cells
in the process too.
Large-scale clinical-end point trials are now needed to assess the effect of intracoronary infusion of bone marrow cells
on morbidity and mortality in patients," said Dr.
THOUSANDS of liver failure patients have been offered hope by a treatment that uses bone marrow cells
to repair damage.
Biodegradable conduits or patches seeded with autologous bone marrow cells
remained patent and functioned well in the pulmonary circulation, with no evidence of aneurismal change or calcification, reported Dr.
Dr Helmut Drexler, from the University of Freiburg, who led the research, said, 'Our results lend support to the concept that autologous (patient's own) bone marrow cells
can be used to enhance left-ventricular functional recovery in patients after acute myocardial infarction (heart attack).
CELLECT[TM] is a minimally invasive device that utilizes a needle to collect bone marrow cells
from the hip area and then processes the cells so they can be grafted onto the spine.
Also, genetic variations may upset the cellular-environmental homeostasis that protects bone marrow cells
from toxic effects such as those caused by benzene, resulting in altered gene expression.
Selective uptake in leukemia cells and resistance of normal bone marrow cells
has been demonstrated, however the mechanism of selectivity is not known.