effect

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References in periodicals archive ?
As a result, when [Cl.sup.-] is present in the solution, at a concentration 100 mM, the Bohr effect of the two mutants containing [beta]Ala93 is significantly modified being practically absent below pH 7.4.
It exhibits normal oxygen affinity with normal cooperativity, Bohr effect, and 2,3-DPG interactions.
Binding of [CO.sub.2] together with [O.sub.2] in arterial blood has been suggested to support pigment function on the venous side in sepioid species (Brix et al., 1981), where both [O.sub.2] and [CO.sub.2] are released, and this [CO.sub.2] helps to exploit the large Bohr effect. In squid, supplementary oxygen uptake via the skin supports the excessive oxygen demand and provides the excess [CO.sub.2] required for the Bohr effect to function (Portne r, 1994).
Clinically, Hb Wayne leads to an increased oxygen affinity Hb with noncooperativity and a markedly reduced Bohr effect. Hb Wayne Asn and Hb Wayne Asp exhibit differences in their carbon monoxide-binding properties (4).
The hemoglobin has a very high and temperature-sensitive oxygen affinity, with no cooperativity or Bohr effect. These properties are adaptive for an animal living in a low-oxygen environment in which the primary function of the hemoglobin is most likely oxygen acquisition to support aerobic respiration.