But there are nuances to Benning's "flatness"; this view of a world of blunted affect
is not totalizing, as her work's limited dimensionality actually heightens her portrayal of subjectivity.
The woman kept her appointment the day after her discharge, but it was noted she had been unable to fill her prescription for Seroquel, a psychotropic agent used to treat schizophrenia, was obsessed with psychotic thoughts, was frightened, and had an "inappropriate and blunted affect
." Two days later she committed suicide in her apartment.
But significant weight gain occurred in 12 patients; sedation, drooling, and blunted affect
were also seen.
Some of these changes include blunted affect
, poor concentration, impaired short- and long-term memory, apathy, social withdrawal, avoidance of complex tasks, and personality changes.
These include flat or blunted affect
(i.e., lack of emotional expression), apathy, and social withdrawal.
Psychiatric practitioners are fully cognizant of the extensive clinical variability in patients with schizophrenia, including the presence, absence, or severity of various signs and symptoms, such as insight, delusions, hallucinations, conceptual disorganization, bizarre behaviors, emotional withdrawal, agitation, depression, suicidality, anxiety, substance use, somatic concerns, hostility, idiosyncratic mannerisms, blunted affect
, apathy, avolition, self-neglect, poor attention, memory impairment, and problems with decision-making, planning ahead, or organizing one's life.
The primary endpoint was the mean change from baseline to day 28 on the 30-item Positive and Negative Syndrome Scale (PANSS) total score, which measures positive symptoms such as delusions, suspiciousness, and hallucinations; negative symptoms, such as blunted affect
, social and emotional withdrawal, and stereotyped thinking; and general psychopathology, such as anxiety, tension, depression, and active social avoidance.