beta cell

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  • noun

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a cell that produces insulin in the isles of Langerhans in the pancreas

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They identified the signals that instruct mouse progenitor cells to become cells that make tubes and later insulin-producing beta cells.
While alpha cells converting into beta cells had been described before, this was the first time an existing drug had been reported to stimulate the process and it caused a lot of excitement in the field, Huising said.
6 As diabetes-induced oxidative stress disturbs the pancreatic endocrine-endothelial axis, it seems axiomatic that use of antioxidants can hamper the diabetes-induced oxidative injury and protect beta cells and endothelial cells.
In addition, Sanofi and Evotec also aim to use human beta cells for high-throughput drug screening to identify small molecules or biologies beneficial for beta cell activity, treatment options are available.
Sanofi and Evotec will also incorporate human beta cells in the process for high-throughput drug screening to identify small molecules or biologics beneficial for beta cell activity.
In a healthy pancreas, beta cells detect sugar in the blood and release insulin when the levels get too high.
Fasting glucose, pancreatic beta cell function, insulin sensitivity and resistance, serum zinc, and lipids were measured at the beginning and end of the study.
Evidence for proteotoxicity in beta cells in type 2 diabetes: Toxic islet amyloid oligomers from intracellularly in the secretory pathway.
During type 1 diabetes, killer T-cells are thought to attack pancreatic beta cells.
Loss of insulin-producing beta cells in the pancreas is a hallmark of diabetes.
Serious forms are caused by depletion in pancreatic beta cells and associated loss in insulin s homeostatic control throughout life.
Using human embryonic stem cells as a starting point, experts have for the first time been able to produce human insulin-producing beta cells equivalent in almost every way to normally functioning beta cells in the kind of massive quantities needed for cell transplantation and pharmaceutical purposes.
The multistep protocol, which took 4-5 weeks and treatment with eleven different factors, produced insulin-secreting SC-[beta] cells that produced about half the amount of insulin as normal adult beta cells from the pancreas.
Islets contain beta cells that make insulin, which controls blood sugar levels.