beta cell

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  • noun

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a cell that produces insulin in the isles of Langerhans in the pancreas

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Further research at UIC showed that it was possible to stop the immune attack on pancreatic Beta cells through immunomodulation (regulating a specific immune attack on specific targets).
The stem cell-derived beta cells are presently undergoing trials in animal models, including nonhuman primates.
In this new report, the authors note that global gene expression analysis showed "SC-[beta] cells made ex vivo are most similar, but not completely identical, to cadaveric beta cells.
Fred Levine, of the Sanford Children's Health Research Center at Sanford-Burnham, said that they were able to generate new beta cells, the cells that produce insulin, by introducing caerulein to the pancreas and have potentially freed patients from daily doses of insulin to manage their blood-sugar levels.
If the product candidate performs as intended, it has the potential to provide individuals who have T1D with a replacement for the beta cells lost or impaired as a result of their disease.
When the immune system strikes the beta cells, the attack causes collateral damage to capillaries that carry blood to and from the islets.
One hypothesis is that through directed differentiation, pluripotent stem cells can be differentiated into functional insulin secreting beta cells.
The worse your beta cells perform, the greater your odds of diabetes.
Diminished glucose sensing by beta cells was an important factor in both the development and severity of the disease.
Snapin also is found in the insulin-secreting pancreatic beta cells.
Insulin is synthesised in the beta cells of the pancreas and stored until released by exocytosis.
Royal College of Surgeons' Professor Jochen Prehn said: "There is tremendous hope there is capacity to regenerate beta cells or protect them against immune cell attack.
Type 1 diabetes occurs when the body's immune system attacks and destroys the beta cells in the pancreas, the insulin "factory" of the body.
KEY WORDS: arsenic, diabetes, insulin secretion, Nrf2, oxidative stress, pancreatic beta cells, ROS.
Scientists were surprised to find that new beta cells arose from alpha cells in the pancreas, rather than from stem cells.