Twenty consecutive patients with BLEL, who were diagnosed between January 2012 and December 2013 by histopathologic examination, were observed.
The patients with BLEL in this study were mainly middle-aged females with a male-to-female ratio of 1:4.
Recently, the phenomenon that patients with BLEL have a high level of serum IgG4 has been discussed more and more, and the concept that BLEL is a subtype of IgG4-related sclerosing disease has been increasingly accepted by doctors and scholars.
The fact that hypocomplementemia existed in 45% of patients with BLEL was a very surprising finding, which needs more in-depth research to investigate the relationship between BLEL and hypocomplementemia.
In this study, the lacrimal gland for anti-IgG4 antibody staining, and elevated concentrations of IgG4 were also detected in patients with BLEL.