B lymphocyte


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  • noun

Synonyms for B lymphocyte

a lymphocyte derived from bone marrow that provides humoral immunity

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References in periodicals archive ?
It has been reported that estrogen stimulates T-cell-dependent immunity by activating gene expression on T and B lymphocytes. E2 enhances p-ERK 1/2, p-CREB, and p-Akt gene activations via an ER-dependent mechanism.
If they are activated by a B lymphocyte, the [CD8.sup.+] Tregs will express [CD25.sup.+][CTLA-4.sup.+][FoxP3.sup.+], which suppresses cell proliferation and release of proinflammatory cytokines.
Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis.
In accordance with these results, the above-described outcomes for T and B lymphocytes have been observed in several immunological diseases and have also provided opportunities to selectively modulate specific immune functions by targeting glucose, lipid, and amino acid metabolism [10].
In addition to stimulating B lymphocytes, Th2 cells suppress the cytotoxic T lymphocyte response, decreasing the robustness of cell-mediated immunity.
The T4 cells in turn stimulate antibody production by B lymphocytes. Together the activated macrophages, B lymphocytes, and antibodies form granulomas in the affected tissue.
Humoral: part of the immune response that involves antibodies secreted by B lymphocytes (see below) and circulating in body fluids such as blood or lymph.
These T lymphocytes activate and release messenger substances (cytokines) that increase the immune response and stimulate the production of antibodies by B lymphocytes. Other types of T lymphocytes have a direct cytotoxic action on cells presenting parasite fragments, thus completing the immune response.
Bristol-Myers Squibb Company (Princeton, NJ) has patented antibody heteroconjugates and bispecific antibodies and methods and compositions and their use in the enhancement or inhibition of activation and function of T or B lymphocytes. The heteroconjugates are comprised of at least two antibody molecules cross-linked to each other, each molecule being reactive with a different lymphocyte antigen on the same cell.