Other drugs used for severe organ involvement include mycophenolate (CellCept) and azathioprine (Azasan
A Cochrane systematic review identified 13 randomized controlled trials enrolling a combined 1022 patients with psoriatic arthritis randomly assigned to receive a DMARD--methotrexate, sulfasalazine (Azulfidine), azathioprine (Imuran/ Azasan
), or etretinate (Tegison; no longer available in the US)--compared with placebo.
For treatment of lung fibrosis, some success has been reported with the use of an immunosuppressive drug such as cyclophosphamide (Cytoxan), azathioprine (Azasan
) or mycophenolate mofetil (CellCept).
Salix also markets XIFAXAN, VISICOL, OSMOPREP, AZASAN
, ANUSOL-HC and PROCTOCORT.
Less commonly used is azathioprine (Imuran, Azasan