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Related to Autoantigens: Autoimmune reaction
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  • noun

Words related to autoimmunity

production of antibodies against the tissues of your own body

References in periodicals archive ?
The HLA-DQ8 allele is one such gene known to predispose individuals that carry it for T1D by mis-presenting autoantigens that favor the generation and function of harmful, but not protective, immune cells.
Determination of three major islet autoantigens - insulin, GAD65, and ICA512 (IA-2) - has become central component of studies of the natural history of DM.
Previously, we have described 81 autoantigens identified from breast, colon, and thyroid cancers by SEREX approach [10, 12, 13, 15, 16].
Some of the autoantigens involved in the pathogenesis of RA include IgG, collagen, proteoglycan, citrullinated proteins, fibrin, fibrinogen, and the shared human leukocyte antigen (HLA) DR epitope [6, 7].
12) On the other hand, the association between pathology and citrullinated autoantigens is poorly defined because clinical laboratory testing of sera from RA patients is dependent on an artificial cycliccitrullinated peptide that could react with multiple citrullinated self-proteins.
Beta cells can also release autoantigens that could start or increase an autoimmune reaction, "especially in genetically predisposed people,'' Ludviggson added.
So along with the macrophages, Chen and colleagues injected the mice with the previously attacked body proteins, called autoantigens.
T cells that express the transcription factor Foxp3 restrains immune responses against autoantigens.
Mechanisms of disease: Autoantigens as clues to the pathogenesis of myositis.
4) These disorders are characterized by inflammation and production of an extensive variety of autoantibodies detected against multiple autoantigens.
Type-1 diabetes (T1D) is an autoimmune disease in which pancreatic E--cells are gradually destroyed by autoreactive T-cells recognising autoantigens (Auto-Ag) such as GAD65 and insulin.
It may prevent autoimmunity by masking the autoantigens from the immune system or increasing their clearance [24].
Immunologically, the inflammatory process is thought to be mediated by T-cell and B-cell responses to CNS autoantigens.
Nanoengineering autoantigens to prevent and treat autoimmunity; and
Betterle C, Dal Pra C, Mantero E Zanchetta R: Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: autoantibodies, autoantigens, and their applicability in diagnosis and disease prediction.