No effect of atypical antipsychotic
drugs on weight gain and risk of developing type II diabetes or lipid abnormalities among nursing home elderly patients with Alzheimer's disease.
5,6) The major atypical antipsychotic
agents currently available in the United States are listed in TABLE 1.
If uncontrollable behavior can't be addressed in any other way, and if risks and benefits of using the medication with a particular patient have been carefully weighed, treatment with an atypical antipsychotic
may be indicated, Dr.
The addition of an atypical antipsychotic
can control the psychosis without altering the anti-Parkinson's medication, thus preserving the patient's motor function.
drugs as a first-line treatment of schizophrenia: a rationale and hypothesis.
The findings from the Pharmacor topic entitled Bipolar Disorder reveal that atypical antipsychotics
make up the majority of sales in this market, with more than $5.
If the product is approved it will be the first and only long-acting, atypical antipsychotic
that has a dosing schedule of four times a year.
Although the atypical antipsychotics
are recommended as first-line treatment for schizophrenia, the typical antipsychotics have demonstrated comparable efficacy for the positive symptoms of schizophrenia and are still widely prescribed.
In particular, there is no good evidence to support the use of atypical antipsychotics
for substance abuse disorder, eating disorders, or insomnia.
The National Pregnancy Registry for Atypical Antipsychotics
is collecting data to investigate the safety of atypical antipsychotics
during pregnancy, when these agents are used to treat a wide range of mood, anxiety, or psychiatric disorders, according to the announcement from the hospital.
Effectiveness of atypical antipsychotic
drugs in patients with Alzheimer's disease.
Of the 17 randomized atypical antipsychotic
trials that the FDA reviewed, 15 found a significantly increased risk of death--usually cardiovascular or infectious--among elderly, demented patients taking the drugs, compared with placebo.
A fourth atypical antipsychotic
, olanzapine, yielded slightly more reduction in symptoms than the other drugs did.
The findings, from the analysis of patient-level claims data from the fourth quarter of 2010, suggest that failure of a branded selective serotonin reuptake inhibitor (SSRI) or serotonin/norepinephrine reuptake inhibitor (SNRI) will result in a switch to an atypical antipsychotic
rather than a switch within or between antidepressant drug classes.
The company said ALKS 3831 is a novel oral atypical antipsychotic
drug candidate designed to be a broad spectrum treatment for schizophrenia.