sup] A highly sensitive and specific blood biomarker or protein profile could provide information on the stability and vulnerability of carotid atherosclerotic plaques
though such a discovery has yet to be made.
We found the age of patients in two subgroups was significantly higher than the non-plaque group, this demonstrates that the formation of atherosclerotic plaques
may be closely correlated to the age of patients.
Pycnogenol[R] has been demonstrated to slow the progression of atherosclerotic plaques
Collagens are the most abundant constituent of the extracellular matrix in atherosclerotic plaques
and play a crucial role in keeping the atherosclerotic plaques
intact and stable.
Because previous studies have identified cleaved caspase-3 in both human  and mouse  atherosclerotic plaques
, where it colocalizes with dead macrophages and lipid-rich plaque components , we aimed to investigate the impact of caspase-3 deletion on atherogenesis by crossbreeding caspase-3 knockout ([Casp3.
Tissue samples were obtained from atherectomy of coronary artery or carotid atherosclerotic plaques
by surgeon during CABG.
IVUS also seems to be capable of quantifying atherosclerotic plaques
as well as positive and negative vascular remodeling.
The chain of reasoning is as follows: The biomarker of plaque instability is found in atherosclerotic plaques
and is more abundant in plaques with unstable characteristics than in plaques with stable characteristics an increased concentration of the biomarker in the circulation signals that the patient has plaques with unstable characteristics that are more prone to rupture; and plaque rupture leads to unstable angina or AMI.
They found that several bacteria were found in the atherosclerotic plaques
and, primarily, the mouth, but also the gut, of the same patient and that the bacteria Pseudomonas luteola and Chlamydia pneumoniae were present in all atherosclerotic plaques
The first study, presented by cardiology fellow Nikolaos Alexopoulos, MD, now at the University of Athens, Greece, showed that patients with a larger volume of epicardial adipose tissue tend to have the types of atherosclerotic plaques
cardiologists deem most dangerous: non-calcified plaques.
This finding, together with the absence of atherosclerotic plaques
in some patients with high FRS, suggests that the use of routine clinical predictors may be insufficient for identifying patients who might benefit from aggressive risk factor modification, Dr.
These include beneficial effects in endothelial function and blood flow, decreasing LDL oxidation, enhancing the stability of atherosclerotic plaques
, inhibiting vascular smooth muscle cells proliferation and platelet aggregation, and reducing vascular inflammation (23).
The underlying rationale is that a greater understanding of the cellular and molecular pathogenesis of high risk plaques, along with the ability to visualize and diagnose these lesions, can lead to more effective management of acute coronary syndromes, which are primarily caused by the instability of atherosclerotic plaques
This risk is the result of increased inflammation in atherosclerotic plaques
, contributing to plaque rupture.
And the fifth was Opn, which transcribes osteopontin, a protein involved in the mineralization of bone and a component of human atherosclerotic plaques