Strokes can be either haemorrhagic, caused for instance by a bursting aneurysm (accounting for 20% of all strokes) or they can be occlusive, possibly resulting from a thrombosis on an atheromatous plaque
This kind of management would go a long way toward reducing the risk of PAD progression and may even help to induce atheromatous plaque
There is a special class of SCAD, which develops on a preexisting atheromatous plaque
Borean has already demonstrated that trimerised APO A-I is able to stabilise and inhibit atheromatous plaque
formation in mice arteries more effectively than the naturally occurring monomeric form.
Antrin selectively targets and accumulates in metabolically active inflammatory cells, such as macrophages in atheromatous plaque
," said Dr.
In type II variant spasm of coronary artery may result in atheromatous plaque
disruption and thus manifests as an acute myocardial infarction.
Before joining CAT, Dr Osbourn was a British Heart Foundation Postdoctoral researcher at the Departments of Biochemistry and Medicine in Cambridge [where she played a significant role in identifying genes up-regulated in atheromatous plaque
Recent studies from our group suggest that neopterin may provide more comprehensive information regarding risk of cardiovascular events than do CRP measurements, particularly when macrophage activation is implicated, as seen in rapid CAD progression (5) and atheromatous plaque
The inflammatory process might encourage more extensive atheromatous plaque
formation and hence larger infarct size than in nonarthritic individuals who develop acute MI, he said.
rupture and subsequent thrombosis are the main causes of acute coronary syndrome (ACS) including acute myocardial infarction (AMI), unstable angina pectoris (UAP), and sudden cardiac death (1, 2).
Investigators noted a 34% reduction in levels of IL-6, a cytokine released from blood cells in response to inflammatory stimuli that is believed to be responsible for the induction of CRP production by the liver, and a 50% reduction in levels of MMP-9, an enzyme thought to cause destabilization of atheromatous plaque
, leading to clot formation.
MUNICH -- Nifedipine improves coronary endothelial function without significantly reducing atheromatous plaque
size in patients with stable coronary artery disease, Dr.
In addition to causing gum disease, MMPs thin the fibrous cap overlying atheromatous plaque
, thereby increasing the risks of acute MI and unstable angina in patients with coronary artery disease.
Biochemical composition of atheromatous plaques
and changes in blood composition will be investigated.
Optical coherence tomography imaging of cholesterol crystals demonstrated linearly oriented, highly reflecting structures within atheromatous plaques