In reality, patients who took Atabrine
had so many complaints about its many negative side effects that they found nothing funny about it.
Like the British, the Americans relied primarily upon Atabrine
(Mepacrine) to suppress and control malaria.
A synthetic substitute, Atabrine
, was developed in the US, but an even better drug was made in Germany and when it fell into American hands at the end of the war, the US army copied it and developed the cholorquine compound.
Specific antimalarials used to treat lupus include hydrochloroquine (Plaquenil), chloroquine (Aralen), and quinacrine (Atabrine
We missionaries took our atabrine
and aralen religiously, but the Venezuelans were not so careful.
Toxic psychosis following Atabrine
. Bull US Army Med Dept 1945; 86:63-9.
Instead, the US military made do with the exceptionally unpleasant medicine atabrine
. Originally a German drug produced in the United States prior to the war, atabrine
was more effective in smaller doses than quinine, which has been used for 200 years.