Patients' demographic, polysomnographic and ophthalmologic characteristics according to apnea-hypopnea index
Control Mild OSAS (n=50) (n=15) Gender (n, %) Female 22 (44) 6 (40) Male 28 (56) 9 (60) Age (years) 46.
Out of 48 patients 7(14%), 3(6%), 2(4%), 1(2%) patients in the age group of 20-40 had apnea-hypopnea index
less than 5, 5-14, 15-29 and equal or more than 30 respectively, similarly 16(32%), 5(10%), 4(8%), 2(4%) patients in the age group of 40-60 had apnea-hypopnea index
less than 5, 5-14, 15-29 and equal or more than 30 respectively.
Major finding: Nearly half (49%) of the 45 patients receiving active treatment with the device had an apnea-hypopnea index
that was lower than 5, compared with 11% of those using the placebo device, for an odds ratio of 7.
In adults, an apnea-hypopnea index
(AHI) of greater than or equal to 5 is the minimum criterion for establishing a sleep-disordered breathing diagnosis, while severity is classified by the number of events per hour.
Inclusion criteria were: OSA, apnea-hypopnea index
10 or greater; control, apnea-hypopnea index
less than 5.
Investigators rated 42 of them as having moderate to severe OSA based on an apnea-hypopnea index
in excess of 5 events/hr.
1) The syndrome is defined as an apnea-hypopnea index
(AHI) of 5 or more events per hour during a sleep polysomnogram, accompanied by either excessive daytime sleepiness or 2 of the following: choking or gasping during sleep, recurrent awakenings from sleep, daytime fatigue, and impaired concentration.
Spearman correlation analysis was applied between the QTD, QTcD and Apnea-Hypopnea Index
The sleep study, as measured by the apnea-hypopnea index
, showed a positive trend (p=0.
It is the only portable device providing Apnea-Hypopnea Index
(AHI), Respiratory Disturbance Index (RDI), and Oxygen Desaturation Index (ODI) based on actual sleep time and sleep states (REM/Wake/Deep/Light) without a cumbersome nasal cannula or belt around the chest.
Treatment success was defined as a [greater than or equal to] 50% reduction from baseline in the apnea-hypopnea index
(AHI) or AHI <10 when wearing MAD.
Of these, 43 patients without OSA were compared with 43 patients with OSA defined as an apnea-hypopnea index
(AHI) of at least 15.
5) On the other hand, in cases where a patient has an Apnea-Hypopnea Index
(AHI; used to indicate the severity of sleep apnea) score of more than five, a positive ESAP has a predictive power of 100%.
To assess the apnea-hypopnea index
(AHI), the researchers defined disordered-breathing events based on both the >3% and >4% thresholds for oxygen desaturation.