Metabolic Changes: Atypical antipsychotic drugs
have been associated with metabolic changes that may increase cardiovascular/cerebrovascular risk.
According to CRI's investigation on Chinese sample hospital market, the CAGR of sales revenue of aripiprazole was about 40% from 2007 to 2012, which was higher than the overall growth rate of antipsychotic drug
market in China.
There is another reason for this increase in the number of antipsychotic drugs
being prescribed to children, according to the Centers for Disease Control.
Department of Health and Human Services, Office of the Inspector General, Medicare Atypical Antipsychotic Drugs
Claims for Elderly Nursing Home Residents, 0E1-07-08-00150 (May 2011).
The prime suspect, due mainly to the therapeutic success of antipsychotic drugs
, is dopamine imbalance.
They found that an enzyme called HDAC2 was highly expressed in the brain of mice chronically treated with antipsychotic drugs
, resulting in lower expression of the receptor called mGlu2, and a recurrence of psychotic symptoms.
Posters are being displayed throughout GP surgeries encouraging people with dementia who are taking antipsychotic drugs
to have their prescriptions reviewed as soon as possible.
J&J officials defrauded the state's Medicaid system by wrongfully touting Risperdal as superior to competing antipsychotic drugs
and minimizing its links to diabetes, said jurors in state court in Opelousas, LA.
THE NETHERLANDS -- Data from community-dwelling elderly patients between 1996 and 2006 suggests that both older conventional (first-generation) and the newer atypical (second-generation) antipsychotic drugs
are associated with an increased incidence of pneumonia.
could increase the risk of dangerous blood clots, experts said today.
The alternative to conducting consensus studies, like Gardner et al, requires fixed-dose, randomized trials involving multiple active comparators at a wide range of doses; use of plasma or serum concentrations of antipsychotic drugs
and their major active metabolites; or use of brain imaging memods to estimate levels of receptor occupancy.
A new study, published just last month, found that antipsychotic drugs
prescribed for children between the ages of 2 to 5 doubled over the past decade.
THE use of antipsychotic drugs
in the elderly doubles the risk of potentially fatal pneumonia, researchers said.
Atypical antipsychotic drugs
(AADs) are the preferred and most effective treatments currently available for schizophrenia.
Secondly the authors need to give more emphasis to the Indian setting as well as prospective studies done in Indian patients with psychiatric disorders exposed to antipsychotic drugs