Effects of extracts of Artemisia diffusa against Plasmodium berghei as a new antimalarial agent
BOSTON--The use of adjunctive therapy and a lot of patience may go a long way to improving the response of cutaneous lupus erythematosus to antimalarial agents
, according to Dr.
Avery MA, Muraleedharan KM, Desai PV, Bandyopadhyaya AK, Furtado MM, Tekwani BL (2003) Structure-activity relationships of the antimalarial agent
Earlier an in vitro study also found combination of quinine and omeprazole to be significantly synergistic (8), similarly another in vitro study found rabeprazole and lansoprazole to be the most effective antimalarial agents
amongst the available PPI (7).
The article, "High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent
artemisinin, in Escherichia coli" appears in PLoS ONE, an open-access journal from the Public Library of Science.
The development of simple and cost-effective analytical protocols for artemisinin and its derivatives in both pure form and in dosage form has become very important in the face of increasing supply and demand for this antimalarial agent
Sold under the brand name Maloff Protect,l the tablets contain two antimalarial agents
, atovaquone and proguanil.
8) Due to this serious health problem, researchers have focused on discovering new antimalarial agents
In-vitro activity of pyronaridine and amodiaquine against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial agents
Zhang, Synthesis and Evaluation of 4-Quinazolinone Compounds as Potential Antimalarial Agents
Masterson also deftly handles many subthemes throughout the book including: how a dawning appreciation for medical ethics eventually eliminated malaria experiments in humans, how the infrastructure created to fight malaria eventually became the National Institutes of Health, how pharmaceutical companies were involved in the search for antimalarial agents
, and how current malaria-control programs in endemic countries work (or don't--even today, two African children die from malaria per minute).
The antimalarial agents
mefloquine and chloroquine and the combinations atovaquone/proguanil and pyrimethamine/sulfadoxine can, at doses used for prophylaxis, be administered together with the Ty21a vaccine; however, the manufacturer advises that other antimalarial agents
only be administered at least 3 days after the last vaccine dose (27).
These slow-acting medications include a potpourri of agents from different pharmacologic classes including immunosuppressive agents, specific anti-cytokine agents, antimalarial agents
, chelating agents and even gold compounds.
Synthesis and evaluation of cryp-tolepine analogues for their potential as new antimalarial agents
In the context of increasing resistance of Plasmodium spp to chloroquine and other antimalarial agents
such as sulfadoxinepyrimethamine, (4) the quest for a malaria vaccine has been long and sombre but recent development in medical research has led us to the point where we can consider the development of a vaccine to be feasible.